The Effect of Topical Vitamin D and Olive Oil on Xerosis and Pruritus in HD Patients
DOI:
10.29303/jppipa.v10i11.8779Published:
2024-11-25Issue:
Vol. 10 No. 11 (2024): NovemberKeywords:
CKD, Hemodialysis, Pruritus, XerosisResearch Articles
Downloads
How to Cite
Downloads
Metrics
Abstract
The kidneys are essential organs maintaining the body's stability. Chronic Kidney Disease (CKD) causes 850,000 deaths yearly, ranking it 12th among global causes of death. This number is projected to rise, reaching 14 per 100,000 people by 2030. This study used a quantitative quasi-experimental design with a one-group pretest-posttest approach from June 13 to July 13, 2024. The study involved 42 respondents, and paired t-test analysis revealed significant effects of applying topical Vitamin D and olive oil on xerosis and pruritus in hemodialysis patients in West Java hospitals (T-Count: 23.854 > T-table: 0.462, p-value: 0.045). Most respondents were aged over 50 (66.9%) and predominantly male (61.9%). Hemodialysis duration varied, with 32.3% treated for less than 12 months and 47.7% for over 12 months. Comorbidities were present in 88% of respondents. After treatment, no patients reported severe itching from xerosis or pruritus. In conclusion, the study shows that topical Vitamin D and olive oil significantly reduce xerosis and pruritus in hemodialysis patients in West Java (p-value: 0.045).
References
Albuquerque, P. B. S., de Oliveira, W. F., dos Santos Silva, P. M., dos Santos Correia, M. T., Kennedy, J. F., & Coelho, L. C. B. B. (2022). Skincare application of medicinal plant polysaccharides — A review. Carbohydrate Polymers, 277(October 2021), 118824. https://doi.org/10.1016/j.carbpol.2021.118824
Barcelos, R. C. S., de Mello-Sampayo, C., Antoniazzi, C. T. D., Segat, H. J., Silva, H., Veit, J. C., Piccolo, J., Emanuelli, T., Bürger, M. E., Silva-Lima, B., & Rodrigues, L. M. (2015). Oral supplementation with fish oil reduces dryness and pruritus in the acetone-induced dry skin rat model. Journal of Dermatological Science, 79(3), 298–304. https://doi.org/10.1016/j.jdermsci.2015.06.015
Brunelli, L., Bravo, G., Romanese, F., Righini, M., Lesa, L., De Odorico, A., Bastiani, E., Pascut, S., Miceli, S., & Brusaferro, S. (2022). Sexual and reproductive health-related knowledge, attitudes and support network of Italian adolescents. Public Health in Practice, 3(February), 100253. https://doi.org/10.1016/j.puhip.2022.100253
Castro, C. A., Monterrosa-Blanco, A., Rodríguez, L. L., Castiblanco, A., Bernal, L., Ladino, M. J., Pinilla, D., Melo, C., & Baquero, F. (2024). Knowledge and attitudes regarding contraceptive methods and sex education in students and parents of eight Colombian schools 2020–2021: a mixed methods study. The Lancet Regional Health - Americas, 30, 100678. https://doi.org/10.1016/j.lana.2024.100678
Cooper, C. M., Ahmed, S., Winch, P. J., Pfitzer, A., McKaig, C., & Baqui, A. H. (2014). Findings from the use of a narrative story and leaflet to influence shifts along the behavior change continuum toward postpartum contraceptive uptake in Sylhet District, Bangladesh. Patient Education and Counseling, 97(3), 376–382. https://doi.org/10.1016/j.pec.2014.09.007
Donker, A. E., van der Staaij, H., & Swinkels, D. W. (2021). The critical roles of iron during the journey from fetus to adolescent: Developmental aspects of iron homeostasis. Blood Reviews, 50(July), 100866. https://doi.org/10.1016/j.blre.2021.100866
Duane, M., Martinez, V., Berry, M., & Manhart, M. D. (2022). Evaluation of a fertility awareness-based shared decision-making tool part 1: Study design and impact on clinician knowledge. PEC Innovation, 1(February), 100061. https://doi.org/10.1016/j.pecinn.2022.100061
Fauzi, A., & Triaswati, R. (2021). The effect of intradialytic stretching training on restless legs syndrome and sleep quality in hemodialysis patients. Korean Journal of Adult Nursing, 33(1), 37–43. https://doi.org/10.7475/kjan.2021.33.1.37
Field, M. S., Bailey, R. L., Brannon, P. M., Gregory, J. F., Lichtenstein, A. H., Saldanha, I. J., & Schneeman, B. O. (2022). Scanning the evidence: process and lessons learned from an evidence scan of riboflavin to inform decisions on updating the riboflavin dietary reference intakes. American Journal of Clinical Nutrition, 116(2), 299–302. https://doi.org/10.1093/ajcn/nqac102
Gelagay, A. A., Worku, A. G., Bashah, D. T., Tebeje, N. B., Gebrie, M. H., Yeshita, H. Y., Cherkose, E. A., Ayana, B. A., Lakew, A. M., Asmamaw, D. B., Negash, W. D., Belachew, T. B., Fentie, E. A., & Bitew, D. A. (2023). Factors affecting birth interval among mothers in Dabat district, Amhara Regional state, Northwest Ethiopia: A community-based cross-sectional study, 2022. Heliyon, 9(6), e17046. https://doi.org/10.1016/j.heliyon.2023.e17046
Higurashi, S., Tsujimori, Y., Nojiri, K., Toba, Y., Nomura, K., & Ueno, H. M. (2023). Dietary Patterns Associated with General Health of Breastfeeding Women 1–2 Months Postpartum: Data from the Japanese Human Milk Study Cohort. Current Developments in Nutrition, 7(1), 100004. https://doi.org/10.1016/j.cdnut.2022.100004
Khorsand, A., Salari, R., Noras, M. R., Saki, A., Jamali, J., Sharifipour, F., Mirmoosavi, S. J., & Ghazanfari, S. M. (2019). The effect of massage and topical violet oil on the severity of pruritus and dry skin in hemodialysis patients: A randomized controlled trial. Complementary Therapies in Medicine, 45(March), 248–253. https://doi.org/10.1016/j.ctim.2019.06.015
Kloter, E., Albanese, F., Schweighoffer, R., & Wolf, U. (2023). Phytotherapy in paediatric skin disorders – A systematic literature review. Complementary Therapies in Medicine, 74(March), 102942. https://doi.org/10.1016/j.ctim.2023.102942
Kschonsek, J., Stimming, M., Libuda, L., Kersting, M., & Böhm, V. (2016). Food-based modification of LC-PUFA concentration in complementary food did not affect plasma vitamin E concentration in infants. NFS Journal, 3, 25–32. https://doi.org/10.1016/j.nfs.2016.02.005
Leocata, A. M., Kaiser, B. N., & Puffer, E. S. (2021). Flexible protocols and paused audio recorders: The limitations and possibilities for technologies of care in two global mental health interventions. SSM - Mental Health, 1(September), 100036. https://doi.org/10.1016/j.ssmmh.2021.100036
Litvin, K., Grandner, G. W., Phillips, E., Sherburne, L., Craig, H. C., Phan, K. A., Patel, A. N., & Dickin, K. L. (2024). How Do Social and Behavioral Change Interventions Respond to Social Norms to Improve Women’s Diets in Low- and Middle-Income Countries? A Scoping Review. Current Developments in Nutrition, 8(6), 103772. https://doi.org/10.1016/j.cdnut.2024.103772
Lu, Y. T., Chen, C. P., Sun, F. J., Chen, Y. Y., Wang, L. K., & Chen, C. Y. (2024). Associations between first-trimester screening biomarkers and maternal characteristics with gestational diabetes mellitus in Chinese women. Frontiers in Endocrinology, 15(August), 1–9. https://doi.org/10.3389/fendo.2024.1383706
Morris, J. L., & Rushwan, H. (2015). Adolescent sexual and reproductive health: The global challenges. International Journal of Gynecology and Obstetrics, 131, S40–S42. https://doi.org/10.1016/j.ijgo.2015.02.006
Muala, W. C. B., Charnelle, T. K., Fabrice, T. D., Bernard, T., Ghislain, M. N., & Eric Serge, N. (2024). Formulation of weaning food from yellow maize (Zea mays L.) and red millet (Eleusine coracana L.), enriched with pretreated African locust beans (Parkia biglobosa Jacq.) flour. Journal of Agriculture and Food Research, 16(February), 101080. https://doi.org/10.1016/j.jafr.2024.101080
Nisman, W. A., Parmawati, I., Setyoharsih, T. W., Gita, R. V. F., & Annisa, R. (2020). How does health reproduction education based on gender equality influence knowledge, attitudes, and self-efficacy in adolescents? Enfermeria Clinica, 30, 11–15. https://doi.org/10.1016/j.enfcli.2020.09.002
Nurachmah, E., Yona, S., Ismail, R., Afiyanti, Y., Khariroh, S., Surdana, I. K., Sabariah, S., Faisal, M. H., & Toding, J. (2019). Adolescent–parent communication about sexual and reproductive health among junior high school students in five areas with the highest prevalence of HIV in Indonesia: A qualitative study. Enfermeria Clinica, 29(Insc 2018), 194–198. https://doi.org/10.1016/j.enfcli.2019.04.053
Olanbiwoninu, A., Greppi, A., Awotundun, T., Adebayo, E. A., Spano, G., Mora, D., & Russo, P. (2023). Microbial-based biofortification to mitigate African micronutrients deficiency: A focus on plant-based fermentation as source of B-group vitamins. Food Bioscience, 55(March), 102996. https://doi.org/10.1016/j.fbio.2023.102996
Pivatti, A. S. A., Osis, M. J. M. D., & de Moraes Lopes, M. H. B. (2019). “The use of educational strategies for promotion of knowledge, attitudes and contraceptive practices among teenagers – A randomized clinical trial.” Nurse Education Today, 72, 18–26. https://doi.org/10.1016/j.nedt.2018.10.005
Rice, W. S., Redd, S. K., Luke, A. A., Komro, K., Jacob Arriola, K., & Hall, K. S. (2022). Dispersion of contraceptive access policies across the United States from 2006 to 2021. Preventive Medicine Reports, 27(October 2021), 101827. https://doi.org/10.1016/j.pmedr.2022.101827
Rivandi, J., & Yonata, A. (2015). Hubungan diabetes melitus dengan kejadian gagal ginjal kronik. Jurnal Majority, 4(9), 27–34. Retrieved from http://repository.lppm.unila.ac.id/22414/
Saggu, A. K., Tomer, V., Kumar, A., & Pandey, P. (2023). Consideration of Phytonutrients, Probiotics and Prebiotics for enhanced immunity during disaster relief situation – A review. Clinical Nutrition Open Science, 47, 131–146. https://doi.org/10.1016/j.nutos.2022.12.011
Svenvik, M., Raffetseder, J., Brudin, L., Berg, G., Hellberg, S., Blomberg, M., Jenmalm, M. C., & Ernerudh, J. (2024). Early prediction of spontaneous preterm birth before 34 gestational weeks based on a combination of inflammation-associated plasma proteins. Frontiers in Immunology, 15(July), 1–12. https://doi.org/10.3389/fimmu.2024.1415016
Vernon, V., Patel, J., Cieri-Hutcherson, N. E., Arellano, R., Elmore, H., Griffin, B. L., Mitzel, K., Moyeno, W. M., O’Connell, M. B., Pelaccio, K., & Lodise, N. M. (2023). The impact of COVID-19 on select considerations in patients of reproductive age: Brief talking points for pharmacists. Journal of the American Pharmacists Association, 63(3), 720–724. https://doi.org/10.1016/j.japh.2023.01.003
Wood, F. E., Dickin, K. L., Sherburne, L., Diakite, M., Boubacar, A., Pollak, M., & Lundgren, R. (2024). Social Norms: A Missing Ingredient of Programs Seeking to Foster Nutrition Agency. Current Developments in Nutrition, 8(9), 104440. https://doi.org/10.1016/j.cdnut.2024.104440
Xia, Y., Wang, Y., Yuan, S., Hu, J., Zhang, L., Xie, J., Zhao, Y., Hao, J., Ren, Y., & Wu, S. (2024). Development and validation of nomograms to predict clinical outcomes of preeclampsia. Frontiers in Endocrinology, 15(March), 1–12. https://doi.org/10.3389/fendo.2024.1292458
Zhang, Z., Wang, Y., Yang, X., Cheng, Y., Zhang, H., Xu, X., Zhou, J., Chen, H., Su, M., Yang, Y., & Su, Y. (2022). Human Milk Lipid Profiles around the World: A Systematic Review and Meta-Analysis. Advances in Nutrition, 13(6), 2519–2536. https://doi.org/10.1093/advances/nmac097
Author Biographies
Achmad Fauzi, STIKes Abdi Nusantara Jakarta
Rima Yulia, STIKes Abdi Nusantara Jakarta
Tangguh Panji Saputra, STIKes Abdi Nusantara Jakarta
Ajeng Handaru Putri, STIKes Abdi Nusantara Jakarta
Wahyu Agung Dwi Saputra, STIKes Abdi Nusantara Jakarta
License
Copyright (c) 2024 Achmad Fauzi, Rima Yulia, Tangguh Panji Saputra, Ajeng Handaru Putri, Wahyu Agung Dwi Saputra

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with Jurnal Penelitian Pendidikan IPA, agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, web sites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Jurnal Penelitian Pendidikan IPA.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).