Evaluation of Aloe Vera (Aloe barbadensis) Instant Powder on Bone and Tooth Development in Pregnant Women

Authors

Ida Rahmawati , Hapisah , Neny Setiawaty Ningsih , Emilda Sari , Waljuni Astu Rahman , Noor Adha Aprilea

DOI:

10.29303/jppipa.v10i12.9536

Published:

2025-01-05

Issue:

Vol. 10 No. 12 (2024): December

Keywords:

Aloe vera, Bone growth, Calcium, Hematological parameters, Instant powder, Microbial contamination, Phosphorus, Pregnant women, Stability, Tooth development

Research Articles

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Rahmawati, I., Hapisah, Ningsih, N. S., Sari, E., Rahman, W. A., & Aprilea, N. A. (2025). Evaluation of Aloe Vera (Aloe barbadensis) Instant Powder on Bone and Tooth Development in Pregnant Women. Jurnal Penelitian Pendidikan IPA, 10(12), 11211–11218. https://doi.org/10.29303/jppipa.v10i12.9536

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Abstract

This study aimed to evaluate the physical, chemical, biological, stability, and clinical effects of aloe vera (Aloe barbadensis) instant powder on pregnant women. The research involved formulating the powder, assessing its physical properties (flow time, dwell angle, compressibility index), and conducting chemical analysis (phytochemical screening). Microbial contamination was tested using the Most Probable Number and Total Plate Count methods, and stability was assessed over two months. Clinical trials were conducted with two groups: one receiving the aloe vera instant powder and the other receiving calcium supplements (positive control), each consisting of 5 pregnant women for 10 days. The results showed that the powder had a flow time of 8.63 seconds, a dwell angle of 34.33°, and a compressibility index of 7.70%. Chemical screening revealed the presence of flavonoids, phenolics, tannins, saponins, steroids, and interquinones. No microbial contamination was detected, and the powder remained stable. Clinical trials showed a significant increase in red and white blood cells, hemoglobin, potassium, calcium, phosphorus, and magnesium levels in the group receiving the aloe vera instant powder. In conclusion, aloe vera instant powder is stable and enhances hematological parameters and mineral levels in pregnant women.

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The results of the preparation stability test on aloe vera instant powder showed that the flow time in months 0, 1, and 2 was consistent at the 8th second. This indicates that the flow time of the instant powder is stable. There is no flow time change during storage, so it can be declared stable (Saputro & Wardhana, 2021). In the stationary angle parameter, it was found that in the 0th, 1st, and 2nd months, it was consistent at 34°. These results indicate that the instant powder preparation is stable in the stability test. In the compressibility index parameter, it was known that in the 0th, 1st, and 2nd months, it was consistent at 7%. The compressibility index of the powder preparation is stable. The stability test results based on the three physical parameters of the powder preparation showed that the aloe vera instant powder was stable.

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Author Biographies

Ida Rahmawati, Department of Health, Department of Dental Health, Polytechnic of Health Ministry of Health Banjarmasin, South Kalimantan, Indonesia

Hapisah, Polytechnic of Health Ministry of Health Banjarmasin, Banjarmasin

Neny Setiawaty Ningsih, Polytechnic of Health Ministry of Health Banjarmasin, Banjarmasin

Emilda Sari, Polytechnic of Health Ministry of Health Banjarmasin, Banjarmasin

Waljuni Astu Rahman, Polytechnic of Health Ministry of Health Banjarmasin, Banjarmasin

Noor Adha Aprilea, Polytechnic of Health Ministry of Health Banjarmasin, Banjarmasin

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Copyright (c) 2024 Ida Rahmawati, Hapisah, Neny Setiawaty Ningsih, Emilda Sari, Waljuni Astu Rahman, Noor Adha Aprilea

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