Vol. 12 No. 7 (2026)
Open Access
Peer Reviewed

Detection of Tumors and Stages of Mammae Carcinoma on Mammography Imaging Using Morphological Operations

Authors

DOI:

10.29303/jppipa.v12i7.15622

Published:

2026-07-25

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Abstract

Carcinoma of the mammae is disease caused the changing breast cells and forming malignant tumors. Mammography plays an important role as an initial screening method, while histopathological results remain the gold standard for determining the stage of mammary carcinoma. And in the previous method, thresholding limitations did not separate noise, besides that Region Limitation Contrast technique was not good and Active Contour time was relatively long, therefore, Machine learning K-means clustering and Morphological operations became an accurate diagnosis solution through image algorithms, Machine learning have the ability to represent features that have similarities in expert results with Radiologists and even histopathology Results. Able to classify radiography results automatically detect the stage ca mammae and have the same results histopathology. Quasi experimental research on Post-test Only Control Group Design. Build machine learning Matlab program. The test measures accuracy, sensitivity, specificity, positive prediction value and NPV. Data analysis validity test and Wilcoxon statistical test. The study proved that 164 samples obtained good machine learning performance in detecting the stage mammary carcinoma with an accuracy value 97.35%, sensitivity 85.74%, specificity 96.92%, positive prediction value 88.04%, NPV 96.91%, there was similarity between Machine learning and histopathology results.

Keywords:

Automatic detection K-means clustering Mammogram Morphological surgery Stage of mammary carcinoma

References

Al-Antari, M. A., Al-Masni, M. A., Choi, M. T., Han, S. M., & Kim, T. S. (2020). A fully integrated computer-aided diagnosis system for digital X-ray mammograms via deep learning detection, segmentation, and classification. International Journal of Medical Informatics, 137, 104114. https://doi.org/10.1016/j.ijmedinf.2020.104114

Al-Ayyoub, M., Alzu’Bi, S. M., Jararweh, Y., & Alsmirat, M. A. (2017). A GPU-based breast cancer detection system using Single Pass Fuzzy C-Means clustering algorithm. International Conference on Multimedia Computing and Systems -Proceedings, 0, 650–654. https://doi.org/10.1109/ICMCS.2016.7905595 DOI: https://doi.org/10.1109/ICMCS.2016.7905595

AlKandari, M., & Ahmad, I. (2024). Solar power generation forecasting using ensemble approach based on deep learning and statistical methods. Applied Computing and Informatics, 20(3/4), 231–250. https://doi.org/10.1016/j.aci.2019.11.002 DOI: https://doi.org/10.1016/j.aci.2019.11.002

Arry, & Widdo. (2018). Pemanfaatan Ciri Gray Level Co-Occurrence Matrix (GLCM. The Scientific World Journal, 5769–5776. Retrieved from https://j-ptiik.ub.ac.id/index.php/j-ptiik/article/view/3420

Baccouche, A., Garcia-Zapirain, B., Castillo Olea, C., & Elmaghraby, A. S. (2021). Connected-UNets: a deep learning architecture for breast mass segmentation. Npj Breast Cancer, 7(1). https://doi.org/10.1038/s41523-021-00358-x DOI: https://doi.org/10.1038/s41523-021-00358-x

Bhalodiya, J. M., Lim Choi Keung, S. N., & Arvanitis, T. N. (2022). Magnetic resonance image-based brain tumour segmentation methods: A systematic review. Digital Health, 8. https://doi.org/10.1177/20552076221074122 DOI: https://doi.org/10.1177/20552076221074122

Bray, F., Laversanne, M., Sung, H., Ferlay, J., Siegel, R. L., Soerjomataram, I., & Jemal, A. (2024). Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 74(3), 229–263. https://doi.org/10.3322/caac.21834 DOI: https://doi.org/10.3322/caac.21834

Bustan, M. N., Tiro, M. A., & Adiatma. (2018). Modeling of Breast Cancer Diagnosis Classification Based on Hospital Medical Records. Journal of Physics: Conference Series, 1028(1), 1–7. https://doi.org/10.1088/1742-6596/1028/1/012229 DOI: https://doi.org/10.1088/1742-6596/1028/1/012229

Caobelli, F. (2020). Artificial intelligence in medical imaging: Game over for radiologists? European Journal of Radiology, 126, 108940. https://doi.org/10.1016/j.ejrad.2020.108940 DOI: https://doi.org/10.1016/j.ejrad.2020.108940

Egner, J. R. (2010). AJCC Cancer Staging Manual. Jama, 304(15), 1726. https://doi.org/10.1001/jama.2010.1525 DOI: https://doi.org/10.1001/jama.2010.1525

Fan, J., Wang, J., Zhang, C., & Zhang, Y. (2021). Mammogram segmentation using a modified U-Net model. IEEE Access, 9, 99120–99130. https://doi.org/10.1109/ACCESS.2021.3096535

Gbenga, D. E., Christopher, N., & Yetunde, D. C. (2017). Performance Comparison of Machine Learning Techniques for Breast Cancer Detection. Nova Journal of Engineering and Applied Sciences, 6(1), 1–8. Retrieved from www.novaexplore.com

Guo, Y., Zhang, H., Yuan, L., Chen, W., Zhao, H., Yu, Q. Q., & Shi, W. (2024). Machine learning and new insights for breast cancer diagnosis. Journal of International Medical Research, 52(4), 1–29. https://doi.org/10.1177/03000605241237867 DOI: https://doi.org/10.1177/03000605241237867

Halls, S. B. (2019). Potentially malignant microcalcification by texture. Journal of Applied Clinical Medical Physics, 24. Retrieved from https://breast-cancer.ca/malcalctex/

Hasbi, N. A., Adi, K., & Setiawan, A. N. (2022). Early Stadium Detection of Mammae Carcinoma on Mammography Imaging Modality Using K-Means Clustering and Morphological Operations Segmentation Combination. Journal of Medical Imaging and Radiation Sciences, 53(4), S52–S53. https://doi.org/10.1016/j.jmir.2022.10.172 DOI: https://doi.org/10.1016/j.jmir.2022.10.172

He, K., Gkioxari, G., Dollar, P., & Girshick, R. (2017). Mask R-CNN. 2017 IEEE International Conference on Computer Vision (ICCV), 2980–2988. https://doi.org/10.1109/ICCV.2017.322 DOI: https://doi.org/10.1109/ICCV.2017.322

Ibrahim, A., Elshennawy, N. M., & Sarhan, A. M. (2021). Deep learning approach for breast cancer identification in mammograms. IEEE Access, 9, 165507–165520. https://doi.org/10.1109/ACCESS.2021.3134604

Kamil, M. Y., & Salih, A. M. (2019). Mammography images segmentation via Fuzzy C-mean and K-mean. International Journal of Intelligent Engineering and Systems, 12(1), 22–29. https://doi.org/10.22266/IJIES2019.0228.03 DOI: https://doi.org/10.22266/ijies2019.0228.03

Lathifah, A., & Fendriani, Y. (2025). Klasifikasi Penyakit Kanker Payudara pada Citra Mammogram Menggunakan CNN dan Random Forest. Jurnal Online UNJA, 10(3), 95–103. Retrieved from https://www.kaggle.com/datasets/hayder17. DOI: https://doi.org/10.22437/jop.v10i3.43794

Mawaddah, L. (2021). Classification of Benign Tumors and Malignant Tumors On Mammogram Imagery Using Gray Level Co Occurrence Matrix (GLCM) and Support Vector Machine (SVM). The Scientific World Journalechnological. Retrieved from https://www.researchgate.net/publication/356352467

Michael, E., Ma, H., Li, H., Kulwa, F., & Li, J. (2021). Breast Cancer Segmentation Methods: Current Status and Future Potentials. BioMed Research International, 2021, 1–29. https://doi.org/10.1155/2021/9962109 DOI: https://doi.org/10.1155/2021/9962109

Milosevic, M., Jovanovic, Z., & Jankovic, D. (2017). A comparison of methods for three-class mammograms classification. Technology and Health Care, 25(4), 657–670. https://doi.org/10.3233/THC-160805 DOI: https://doi.org/10.3233/THC-160805

Mohammed, A. D., & Ekmekci, D. (2024). Breast Cancer Diagnosis Using YOLO-Based Multiscale Parallel CNN and Flattened Threshold Swish. Applied Sciences, 14(7), 2680. https://doi.org/10.3390/app14072680 DOI: https://doi.org/10.3390/app14072680

Nelda. A, A. R., Setiawan, R., Hendrawan, M. A., Nugroho, D. B., & Hakim, A. N. R. (2024). Deteksi Kanker Payudara Hasil Citra Mammografi menggunakan Metode Convolutional Neural Network (CNN) Arsitektur ResNet-50 Breast Cancer Detection from Mammography Images using Convolutional Neural Network (CNN) Method ResNet-50 Architecture. Jiitu, 01(01), 25–32. Retrieved from https://share.google/sdq2wcj82x0YIht7L

Polat, H., & Mehr, H. D. (2019). Classification of pulmonary CT images by using hybrid 3D-deep convolutional neural network architecture. Applied Sciences (Switzerland), 9(5). https://doi.org/10.3390/app9050940 DOI: https://doi.org/10.3390/app9050940

Salih, A. M., & Kamil, M. Y. (2018). Mammography image segmentation based on fuzzy morphological operations. Proceedings - 2018 1st Annual International Conference on Information and Sciences, AiCIS 2018, 40–44. https://doi.org/10.1109/AiCIS.2018.00020 DOI: https://doi.org/10.1109/AiCIS.2018.00020

Salloum, S. (2025). K-Means Clustering and Classification of Breast Cancer Images Using Histogram of Oriented Gradients Features and Convolutional Neural Network Models: Diagnostic Image Analysis Study. JMIR Formative Research, 9, e71974–e71974. https://doi.org/10.2196/71974 DOI: https://doi.org/10.2196/71974

Shi, P., Zhong, J., Rampun, A., & Wang, H. (2018). A hierarchical pipeline for breast boundary segmentation and calcification detection in mammograms. Computers in Biology and Medicine, 96, 178–188. https://doi.org/10.1016/j.compbiomed.2018.03.011 DOI: https://doi.org/10.1016/j.compbiomed.2018.03.011

Sugiyono, D. (2019). Metode Penelitian Kuantitatif, Kualitatif, dan Tindakan. Alfabeta.

Vaka, A. R., Soni, B., & K., S. R. (2020). Breast cancer detection by leveraging Machine Learning. ICT Express, 6(4), 320–324. https://doi.org/10.1016/j.icte.2020.04.009 DOI: https://doi.org/10.1016/j.icte.2020.04.009

Author Biographies

Nurul Auliyaa Hasbi, Politeknik Muhammadiyah Makassar

Author Origin : Indonesia

Sultan Hamjar, Politeknik Muhammadiyah

Author Origin : Indonesia

Indah Musdalifah, Politeknik Muhammadiyah

Author Origin : Indonesia

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How to Cite

Hasbi, N. A., Hamjar, S., & Musdalifah, I. (2026). Detection of Tumors and Stages of Mammae Carcinoma on Mammography Imaging Using Morphological Operations. Jurnal Penelitian Pendidikan IPA, 12(7), 813–822. https://doi.org/10.29303/jppipa.v12i7.15622