Usage of a Senggani Fruit Vinegar (Melastoma Affine D. Don), to Improve Feed Efficiency and Lower Blood Glucose Levels in Hyperglycemia white Rats (Rattus Norvegicus L.)
DOI:
10.29303/jppipa.v9i6.3418Published:
2023-06-25Issue:
Vol. 9 No. 6 (2023): JuneKeywords:
Blood glucose, Senggani fruit vinegar, RatsResearch Articles
Downloads
How to Cite
Downloads
Metrics
Abstract
Pancreatic beta cells may suffer harm as a result of hyperglycemia. This study examined the effect of Senggani fruit vinegar on blood sugar levels in hyperglycemic white rats. Conditions associated with hyperglycemia may result in an abundance of free radicals, a lack of antioxidants, and damage to pancreatic beta cells. One category of reactive oxygen species (ROS) are the free radicals produced by hyperglycemia. Because the senggani fruit's flavonoids have strong antioxidant properties, they can reduce blood sugar levels. Using a completely randomized design, which was divided into 6 treatments and 4 repeats, this research was applied to the experimental approach. The Variant Analysis algorithm was used to analyze the study's data (ANOVA). Blood glucose levels were among the variables measured. gathered information that explains how giving rats vinegar made from the senggani fruit lowers their blood sugar levels. It is evident that the administration of senggani fruit vinegar (Melastoma affine D. Don) has a positive impact on lowering blood glucose levels in hyperglycemia in white rats (Rattus norvegicus L.).
References
Agustono, A., & Cahyoko, Y. (2019). Feeding with Different Energy on Growth of Grouper (Cromileptes altivelis) Seeds [Feeding with Different Energy To Growth Of Groupers (Cromileptes altivelis)]. Marine and Fisheries Scientific Journal, 1(2), 149-156. https://doi.org/10.20473/jipk.v1i2.11681
Ajie, R. B. (2015). White Dragon Fruit (Hylocereus undatus) Potential as Hyperglycemia Mellitus Treatment. Majority, 4(1), 69-72.
Al-Ishaq, R. K., Abotaleb, M., Kubatka, P., Kajo, K., & Büsselberg, D. (2019). Flavonoids And Their Anti-Diabetic Effects: Cellular Mechanisms And Effects To Improve Blood Sugar Levels. Biomolecules, 9(9), 1-35. https://doi.org/10.3390/biom9090430
Aminah, S., & Yusuf, M. (2015). Efisiensi Pakan, Berat Badan dan Panjang Tulang Tikus yang Mengkonsumsi Kejale selama 6 Minggu. In Prosiding Seminar Nasional & Internasional. Retrieved from https://jurnal.unimus.ac.id/index.php/psn12012010/article/view/1624
Darliana, D. (2011). Management of Nursing Care in Patients with Hyperglycemia Mellitus. Idea Nursing Journal, 2(2), 132-136. https://doi.org/10.52199/inj.v2i2.6371
Dewi, A. C., Widyastuti, N., & Probosari, E. (2020). The Effect of Sorghum (Sorghum bicolor L. Moench) Flour on Fasting Blood Glucose Levels in Diabetic Rats. Journal of Nutrition College, 9(1), 63-70. https://doi.org/10.14710/jnc.v9i1.24266
Hamidatun, H., Mandasari, O. K., Rosdiana, I., & Widiyana, S. D. (2014). Pengaruh cuka salak terhadap penurunan glukosa darah dan histopatologi pankreas tikus diabetes. Program Kreativitas Mahasiswa-Penelitian, 1-6. Retrieved from https://media.neliti.com/media/publications/172273-ID-pengaruh-cuka-salak-terhadap-penurunan-g.pdf
Hardianto, D. (2020). Comprehensive Review of Hyperglycemia Mellitus: Classification, Symptoms, Diagnosis, Prevention, and Treatment: Indonesian Biotechnology & Bioscience (Jbbi), 7(2), 304-317.
https://doi.org/10.29122 /jbbi. v7i2.4209
Hardoko, M., Sasmito, B. B., & Fitriani, E. N. (2020). Study of the Antidiabetic Activity of Mangrove Bedada (Sonneratia alba) Vinegar in Vivo. Jfmr (Journal of Fisheries and Marine Research), 4(3), 399-407. https://doi.org/10.21776/ub.jfmr.2020.004.03.13
Haryoto, H., Nurhardianti, N., Sujono, T. A., Suhendi, A., & Muhtadi, M. (2016). Antidiabetes Mellitus Ekstrak Etanol Kulit Batang Tumbuhan Sala (Cynometra Ramiflora L.) Terhadap Tikus Jantan Galur Wistar yang Diinduksi Aloksan. Prosiding Universty Research Colloquium, 2(1), 113-122. Retrieved from https://publikasiilmiah.ums.ac.id/xmlui/handle/11617/6721
Husna, F., Suyatna, F. D., Arozal, W., & Purwaningsih, E. H. (2019). Experimental Animal Models in Hyperglycemia Research. Pharmaceutical Sciences and Research, 6(3), 131–141. https://doi.org/10.7454/psr.v6i3.4531
Irdalisa, I., Safrida, S., Khairil, K., Abdullah, A., & Sabri, M. (2015). Profil kadar glukosa darah pada tikus setelah penyuntikan aloksan sebagai hewan model hiperglikemik. Jurnal EduBio Tropika, 3(1), 25-28. Retrieved from https://jurnal.usk.ac.id/JET/article/view/5272
Kamalakannan, N., & Prince Psm, (2016). Antihyperglycaemic and Antioxidant Effect of Rutin, A Polyphenolic Flavonoid, in Streptozotocin Induced Diabetic Wistar Rats. Basic & Clinical Pharmacol & Toxicol, 98(1), 97-103. https://doi.org/10.1111/j.17427843.2006.pto_241.x
Kristanti, D., Pratiwi, V. N. R., Rahayu, E. S., & Astuti, M. (2021). Diet of Brown Rice and Parboiled White Rice in Hyperglycemic Rats. Nutrition and Food Research (The Journal of Nutrition and Food Research), 44(2), 93-104. https://doi.org/10.22435/pgm.v44i2.4421
Okon, U. A, Owo, D. U., Udokang, N. E, Udobang, J. A & Ekpenyong, C. E. (2012). Oral administration of aqueous leaf extract of Ocimum Gratissimum Ameliorates Polyphagia, Polydipsia and Weight Loss in Streptozotocin-Induced Diabetic Rats. American Journal of Medicine and Medical Sciences, 2(3), 45-49. https://doi.org/10.5923/j.ajmms.20120203.04
Ousaaid, D., Mechchate, H., Laaroussi, H., Hano, C., Bakour, M., El Ghouizi, A. & El Arabi, I. (2021). Fruits Vinegar: Quality Characteristics, Phytochemistry, And Functionality. Molecules, 27(1), 222-225. https://doi.org/10.3390/molecules27010222
Putra, M. A. D., Jannah, S. N., & Sitaswi, A. J. (2020). Antidiabetic Activity Test of Pineapple Peel Vinegar (Ananas comosus L. Merr.) on Alloxan-Induced Wistar Male White Rats (Rattus norvegicus). Pro-Life Journal, 7(2), 188-197. https://doi.org/10.33541/jpvol6Iss2pp102
Rizah, R. W. (2015). Hypoglycemic effect of winged bean protein extract (Psopharpus tetragonolobus) on Alloxan Induced Diabetic Rats. Scientific Journal of Technoscience, 1(1), 1-6. https://doi.org/10.26877/jitek.v1i1November.831
Roslen, N.A., Alewi, N.A.M., Ahamada, H. And Rasad, M.S.B.A. (2014). Cytotoxicity Screening of Melastoma malabathricum Extracts on Human Breast Cancer Cell Lines In Vitro. Asian Pac J Trop Biomed 4(7), 545-548 https://doi.org/10.12980/APJTB.4.2014C658
Safrida, S., Ulhusna, F. A., Gholib, G., Matualiah, M., Adinda, R., Putri, Y. A., & Fitria, N. (2023). Phytochemical Characterization and Sensory Evaluation of Vinegar from Melastoma malabathricum L. Flowers with Variations in Starter Concentration and Fermentation Time. Jurnal Penelitian Pendidikan IPA, 9(2), 706-713. https://doi.org/10.29303/jppipa.v9i2.2940
Sianturi, E. M., Fuah, A. M., & Wiryawan, K. G. (2016). Study of the addition of tape yeast to feed on consumption, body weight gain, feed conversion ratio, and mortality of rats (Rattus norvegicus). Livestock Media, 29(3). https://doi.org/10.5398/medpet.v29i3.825
Singh, L. K., Karlo, T., & Pandey, A. (2014). Performance of Fruit Extract of Melastoma malabathricum L. Journal Molecular and Biomolecular Spectroscopy, 1(1), 938-943. https://doi.org/10.1016/j.saa.2013.09.075
Wulan, S. N., Astuti, M., Marsono, Y., & Noor, Z. (2012). Testing the Hypoglycemic Effects of Soybeans, Soybean Protein Fractions and Tempeh in Diabetic Rats. Jurnal Teknologi Pertanian, 3(2), 94-102. Retrieved from https://jtp.ub.ac.id/index.php/jtp/article/view/142
Zatalia, S. R., & Sanusi, H. (2013). The Role of Antioxidants in The Pathophysiology, Complications, And Management of Hyperglycemia Mellitus. Acta Medica Indonesiana, 45(2), 141-147. Retrieved from https://europepmc.org/article/med/23770795
Zubaidah, E. (2015). Effects of Apple Vinegar and Salak Vinegar on Decreased Blood Glucose and Pancreatic Histopathology of Wistar Rats with Hyperglycemia. Brawijaya Medicine, 28(4), 297-30. https://doi.org/10.21776/ub.jkb.2015.028.04.7
Author Biographies
Safrida Safrida, Universitas Syiah Kuala
Raissya Adinda, Universitas Syiah Kuala
Muhibbudin, Universitas Syiah Kuala
Khairil, Syah Kuala University
Asiah M.D, Universitas Syiah Kuala
Fitrah Asma Ulhusna, Universitas Syiah Kuala
License
Copyright (c) 2023 Safrida S
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with Jurnal Penelitian Pendidikan IPA, agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, web sites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Jurnal Penelitian Pendidikan IPA.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).