Study of Synergistic Effects of Herbal Meniran (Phyllanthus Niruri L) and Sambiloto (Andrographis Paniculata) as A Substitute Commercial Additive Feed to Improve Immunity Response and Free Chicken Egg Production

Authors

Puji Astuti , Heru Suripta , Diwi Acita Irawati

DOI:

10.29303/jppipa.v9i6.3795

Published:

2023-06-25

Issue:

Vol. 9 No. 6 (2023): June

Keywords:

Bitter, Immune response, Meniran, ND vaccine

Research Articles

Downloads

How to Cite

Astuti, P. ., Suripta, H. ., & Irawati, D. A. . (2023). Study of Synergistic Effects of Herbal Meniran (Phyllanthus Niruri L) and Sambiloto (Andrographis Paniculata) as A Substitute Commercial Additive Feed to Improve Immunity Response and Free Chicken Egg Production . Jurnal Penelitian Pendidikan IPA, 9(6), 4673–4678. https://doi.org/10.29303/jppipa.v9i6.3795

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Abstract

This study aims to look at the immune response and egg production of free-range chickens after ND vaccination by administering meniran and Sambiloto extracts. The design used was a completely randomized design. Data on egg production were analyzed using analysis of variance and data on antibody and lymphocyte titers were analyzed descriptively. The results showed that on D+7 after vaccination, there was an increase in ND antibody and lymphocyte titers and in vaccinated chickens the ND titer was in a protective condition (≥log26), whereas in non-vaccinated chickens, the ND titer and lymphocyte levels were in a less protective condition. On H+28 after the vaccine only the vaccine treatment showed a protective condition, but the administration of meniran and Sambilotol extracts was able to maintain the titer rate longer than without giving Meniran and Sambiloto extracts. Drinking water consumption (Sig.941), feed consumption (Sig.890), egg production (Sig.480) and feed conversion (sig.558) showed no difference. Based on the results of the study, the treatment of vaccines and extracts of meniran and Sambiloto gave a better immune response than without being vaccinated. Administration of meniran and Sambiloto extracts was able to maintain the level of immunity compared to no control.

References

Ali, A., Ponnampalam, E. N., Pushpakumara, G., Cottrell, J. J., Suleria, H. A. R., & Dunshea, F. R. (2021). Cinnamon: A Natural Feed Additive for Poultry Health and Production—A Review. Animals, 11(7), 2026. https://doi.org/10.3390/ani11072026

Astuti, P., & Irawati, D. A. (2022). Broiler Chicken Performance Given Moringa (Moringa oliefera Lam) and Sambiloto (Andrographis paniculata) Leaf Extract in Drinking Water. Jurnal Ilmiah Peternakan Terpadu, 10(1), 92. https://doi.org/10.23960/jipt.v10i1.p92-100

Atun, S., Pertiwi, K. R., Sholikhah, I. Y. M., qolbiah, M., & Safa, S. (2023). Analysis of phenolic content and antioxidant activities of water and ethanol extract of some herbs commonly used as immune boosters. In AIP Conference Proceedings (Vol. 2556, No. 1). AIP Publishing. https://doi.org/10.1063/5.0110915

Gombart, A. F., Pierre, A., & Maggini, S. (2020). A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection. Nutrients, 12(1), 236. https://doi.org/10.3390/nu12010236

Gopalakrishnan, L., Doriya, K., & Kumar, D. S. (2016). Moringa oleifera: A review on nutritive importance and its medicinal application. Food Science and Human Wellness, 5(2), 49–56. https://doi.org/10.1016/j.fshw.2016.04.001

Graeber, D., Schmidt-Petri, C., & Schröder, C. (2021). Attitudes on voluntary and mandatory vaccination against COVID-19: Evidence from Germany. PLOS ONE, 16(5), e0248372. https://doi.org/10.1371/journal.pone.0248372

Habiyah, U., Mutia, R., & Suharti, S. (2015). Performance and Egg Quality of Laying Hens Fed Ration Containing Coriander Seeds (Coriandrum sativum Linn). Media Peternakan, 39(1), 61–66. https://doi.org/10.5398/medpet.2016.39.1.61

Hidayat, R. & Patricia Wulandari. (2022). Potential of Meniran (Phyllanthus niruri L.) and Sambiloto (Andrographis paniculata) as a Supplement to the Management of Coronavirus Disease 2019 (COVID-19). Eureka Herba Indonesia, 3(2), 144–148. https://doi.org/10.37275/ehi.v3i2.58

Hossain, S., Urbi, Z., Karuniawati, H., Mohiuddin, R. B., Moh Qrimida, A., Allzrag, A. M. M., Ming, L. C., Pagano, E., & Capasso, R. (2021). Andrographis paniculata (Burm. f.) Wall. ex Nees: An Updated Review of Phytochemistry, Antimicrobial Pharmacology, and Clinical Safety and Efficacy. Life, 11(4), 348. https://doi.org/10.3390/life11040348

Irwani, N., Zairiful, & Habsari, I. K. (2022). Feed Intake and Feed Conversion Ratio of Broiler Supplemented with Herb Extract. IOP Conference Series: Earth and Environmental Science, 1012(1), 012069. https://doi.org/10.1088/1755-1315/1012/1/012069

Khandia, R., Pathe, C. S., Vishwakarma, P., Dhama, K., & Munjal, A. (2020). Evaluation of the ameliorative effects of Phyllanthus niruri on the deleterious insecticide imidacloprid in the vital organs of chicken embryos. Journal of Ayurveda and Integrative Medicine, 11(4), 495–501. https://doi.org/10.1016/j.jaim.2019.03.003

Khoury, D. S., Cromer, D., Reynaldi, A., Schlub, T. E., Wheatley, A. K., Juno, J. A., Subbarao, K., Kent, S. J., Triccas, J. A., & Davenport, M. P. (2021). Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection. Nature Medicine, 27(7), 1205–1211. https://doi.org/10.1038/s41591-021-01377-8

McCrickerd, K., & Forde, C. G. (2016). Sensory influences on food intake control: Moving beyond palatability. Obesity Reviews, 17(1), 18–29. https://doi.org/10.1111/obr.12340

Nahrul, N. H., Rachmayanti, A. S., & Masaenah, E. (2022). Antibacterial Activity Test of Meniran Herb Extract (Phyllanthus Niruri L.) against Staphylococcus Epidermidis and Klebsiella Pneumoniae. Science Midwifery, 10(5), 3876–3885. https://doi.org/10.35335/midwifery.v10i5.927

Orakpoghenor, O., Ejum Ogbuagu, N., & Sa’Idu, L. (2021). Effect of Environmental Temperature on Water Intake in Poultry. In A. Kumar Patra (Ed.), Advances in Poultry Nutrition Research. IntechOpen. https://doi.org/10.5772/intechopen.95695

Pantaya, D., & Utami, M. M. D. (2018). The blood haematological profile on laying hens that treated by different levels of yeast supplementation. IOP Conference Series: Earth and Environmental Science, 207, 012033. https://doi.org/10.1088/1755-1315/207/1/012033

Rehan, M., Aslam, A., Khan, M.-R., Abid, M., Hussain, S., Umber, J., Anjum, A., & Hussain, A. (2019). Potential Economic Impact of Newcastle Disease Virus Isolated from Wild Birds on Commercial Poultry Industry of Pakistan: A Review. Hosts and Viruses, 6(1). https://doi.org/10.17582/journal.hv/2019/6.1.1.15

Rehman, M. S., Rehman, S. ur, Yousaf, W., Hassan, F., Ahmad, W., Liu, Q., & Pan, H. (2021). The Potential of Toll-Like Receptors to Modulate Avian Immune System: Exploring the Effects of Genetic Variants and Phytonutrients. Frontiers in Genetics, 12, 671235. https://doi.org/10.3389/fgene.2021.671235

Roque, B. M., Venegas, M., Kinley, R. D., de Nys, R., Duarte, T. L., Yang, X., & Kebreab, E. (2021). Red seaweed (Asparagopsis taxiformis) supplementation reduces enteric methane by over 80 percent in beef steers. Plos One, 16(3), e0247820. https://doi.org/10.1371/journal.pone.0247820

Ruesga-Gutiérrez, E., Ruvalcaba-Gómez, J. M., Gómez-Godínez, L. J., Villagrán, Z., Gómez-Rodríguez, V. M., Heredia-Nava, D., Ramírez-Vega, H., & Arteaga-Garibay, R. I. (2022). Allium-Based Phytobiotic for Laying Hens’ Supplementation: Effects on Productivity, Egg Quality, and Fecal Microbiota. Microorganisms, 10(1), 117. https://doi.org/10.3390/microorganisms10010117

Saki, A. A., Khoramabadi, V., Nourian, A. R., & Zamani, P. (2018). Immune response, blood parameters and growth performance in broiler fed reduced protein diet supplemented with β-hydroxy-β-methyl butyrate and conjugated linoleic acid. Acta Scientiarum. Animal Sciences, 40(1), 38000. https://doi.org/10.4025/actascianimsci.v40i1.38000

Sudarman, A., Sumiati, S., & Kaniadewi, R. (2012). Performance of Broiler Chickens Offered Drinking Water Contained Water Extracted Beluntas (Pluchea indica L.) Leaf and Sugar Cane. Media Peternakan, 35(2), 117–122. https://doi.org/10.5398/medpet.2012.35.2.117

Tsujii, H., Miah, A. G., Takeda, I., & Salma, U. (2017). Dietary effect of selenium-enriched radish sprouts, vitamin E, and Rhodobacter capsulatus on hypocholesterolemia and immunity of broiler. Poultry Science Journal, 5(1), 71-81. https://doi.org/10.22069/psj.2017.12411.1233

Usturoi, M. G., Radu-Rusu, R.-M., Usturoi, A., Simeanu, C., Doliș, M. G., Rațu, R. N., & Simeanu, D. (2023). Impact of Different Levels of Crude Protein on Production Performance and Meat Quality in Broiler Selected for Slow Growth. Agriculture, 13(2), 427. https://doi.org/10.3390/agriculture13020427

Zulhendri, F., Chandrasekaran, K., Kowacz, M., Ravalia, M., Kripal, K., Fearnley, J., & Perera, C. O. (2021). Antiviral, Antibacterial, Antifungal, and Antiparasitic Properties of Propolis: A Review. Foods, 10(6), 1360. https://doi.org/10.3390/foods10061360

Author Biographies

Puji Astuti, Universitas Muhammadiyah Karang Anyar

Heru Suripta, Universitas Muhammadiyah Karang Anyar

Diwi Acita Irawati, Universitas Muhammadiyah Karang Anyar

License

Copyright (c) 2023 Puji Astuti, Heru Suripta, Diwi Acita Irawati

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with Jurnal Penelitian Pendidikan IPA, agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, web sites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Jurnal Penelitian Pendidikan IPA.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).