The Effect of Pesticide Exposure on Women Farmers of Reproductive Age on Growth and Development Disorders of Children Born: A Systematic Literature Review

Authors

Friska Eka Fitria , Nur Afrainin Syah , Jamsari , Yuniar Lestari

DOI:

10.29303/jppipa.v9i9.5042

Published:

2023-09-25

Issue:

Vol. 9 No. 9 (2023): September

Keywords:

ADHD, Autism spectrum disorder, Pesticide

Review

Downloads

How to Cite

Fitria, F. E., Syah, N. A. ., Jamsari, J., & Lestari, Y. . (2023). The Effect of Pesticide Exposure on Women Farmers of Reproductive Age on Growth and Development Disorders of Children Born: A Systematic Literature Review . Jurnal Penelitian Pendidikan IPA, 9(9), 596–603. https://doi.org/10.29303/jppipa.v9i9.5042

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Abstract

The large number of children suffering from ADHD and autism today is a result of the increasing use of pesticides in agriculture. This applies to women farmers of childbearing age who work in agricultural settings or women whose work is related to the use of pesticides. Pesticides are a mixture of several chemicals used to control pests and protect plants. With the use of pesticides, yields obtained increased significantly. This study aims to examine the effect of exposure to pesticides on female farmers of childbearing age on growth and development disorders of children born. The review was conducted according to state-of-the-art methods using selected reporting item guidelines for reviews and meta-analyses (PRISMA). We reviewed the literature from several publications and analyzed the effect of exposure to pesticides on female farmers of childbearing age on developmental disorders of the children they were born with. The results of this study are the effect of exposure to pesticides on female farmers of childbearing age on birth defects. The use of pesticides causes pesticide poisoning. Accumulation of pesticides at a certain threshold has a negative impact on the body, namely brain disorders, tumors, cancer, even in pregnant women can cause birth defects. Apart from adults, pesticides also have a negative impact on children

References

Antoniou, E., Rigas, N., Orovou, E., & Papatrechas, A. (2021). ADHD and the Importance of Comorbid Disorders in the Psychosocial Development of Children and Adolescents. Journal of Biosciences and Medicines, 09(04), 1–13. https://doi.org/10.4236/jbm.2021.94001

Athanasiadou, A., Buitelaar, J. K., Brovedani, P., Chorna, O., Fulceri, F., Guzzetta, A., & Scattoni, M. L. (2020). Early motor signs of attention-deficit hyperactivity disorder: A systematic review. European Child & Adolescent Psychiatry, 29(7), 903–916. https://doi.org/10.1007/s00787-019-01298-5

Bai, D., Yip, B. H. K., Windham, G. C., Sourander, A., Francis, R., Yoffe, R., Glasson, E., Mahjani, B., Suominen, A., Leonard, H., Gissler, M., Buxbaum, J. D., Wong, K., Schendel, D., Kodesh, A., Breshnahan, M., Levine, S. Z., Parner, E. T., Hansen, S. N., … Sandin, S. (2019). Association of Genetic and Environmental Factors with Autism in a 5-Country Cohort. JAMA Psychiatry, 76(10), 1035. https://doi.org/10.1001/jamapsychiatry.2019.1411

Barkoski, J. M., Philippe, C., Tancredi, D., Schmidt, R. J., Ozonoff, S., Barr, D. B., Elms, W., Bennett, D. H., & Hertz-Picciotto, I. (2021). In utero pyrethroid pesticide exposure to autism spectrum disorder (ASD) and other neurodevelopmental outcomes at 3 years in the MARBLES longitudinal cohort. Environmental Research, 194, 110495. https://doi.org/10.1016/j.envres.2020.110495

Błażewicz, A., & Grabrucker, A. M. (2022). Metal Profiles in Autism Spectrum Disorders: A Crosstalk between Toxic and Essential Metals. International Journal of Molecular Sciences, 24(1), 308. https://doi.org/10.3390/ijms24010308

Cheng, Z., Hou, Z., Han, H., Yu, X., Li, J., Zhao, Q., Zhang, N., & Lu, Z. (2023). Adsorption, mobility, and degradation of the pesticide propaquizafop in five agricultural soils in China. Scientific Reports, 13(1), 5814. https://doi.org/10.1038/s41598-023-32771-6

Codina-Sola, M., Costa-Roger, M., Pérez-García, D., Flores, R., Palacios-Verdú, M. G., Cusco, I., & Pérez-Jurado, L. A. (2019). Genetic factors contributing to autism spectrum disorder in Williams-Beuren syndrome. Journal of Medical Genetics, 56(12), 801–808. https://doi.org/10.1136/jmedgenet-2019-106080

De La Peña, I. C., Pan, M. C., Thai, C. G., & Alisso, T. (2020). Attention-Deficit/Hyperactivity Disorder Predominantly Inattentive Subtype/Presentation: Research Progress and Translational Studies. Brain Sciences, 10(5), 292. https://doi.org/10.3390/brainsci10050292

DeVilbiss, E. A., Magnusson, C., Gardner, R. M., Rai, D., Newschaffer, C. J., Lyall, K., Dalman, C., & Lee, B. K. (2017). Antenatal nutritional supplementation and autism spectrum disorders in the Stockholm youth cohort: Population-based cohort study. BMJ, j4273. https://doi.org/10.1136/bmj.j4273

Ekinci, Ö. (2019). Clinical correlates of restrictive type Attention Deficit hyperactivity disorder in adolescents. Haydarpasa Numune Training and Research Hospital Medical Journal. https://doi.org/10.14744/hnhj.2019.81557

Faizah, F. (2022). Perilaku impulsive pada anak attention-deficit hyperactivity disorder dengan teknik reprimand dan token economy. Procedia: Studi Kasus Dan Intervensi Psikologi, 10(1). https://doi.org/10.22219/procedia.v10i1.19234

Fiłon, J., Ustymowicz-Farbiszewska, J., & Krajewska-Kułak, E. (2020). Analysis of lead, arsenic and calcium content in the hair of children with autism spectrum disorder. BMC Public Health, 20(1), 383. https://doi.org/10.1186/s12889-020-08496-w

Frye, R. E., Cakir, J., Rose, S., Delhey, L., Bennuri, S. C., Tippett, M., Palmer, R. F., Austin, C., Curtin, P., & Arora, M. (2020). Early life metal exposure dysregulates cellular bioenergetics in children with regressive autism spectrum disorder. Translational Psychiatry, 10(1), 223. https://doi.org/10.1038/s41398-020-00905-3

Gallen, C. L., Anguera, J. A., Gerdes, M. R., Simon, A. J., Cañadas, E., & Marco, E. J. (2021). Enhancing neural markers of attention in children with ADHD using a digital therapeutic. PLOS ONE, 16(12), e0261981. https://doi.org/10.1371/journal.pone.0261981

Genovese, A., & Butler, M. G. (2023). The Autism Spectrum: Behavioral, Psychiatric and Genetic Associations. Genes, 14(3), 677. https://doi.org/10.3390/genes14030677

George, A. (2022). The Connections between Attention-Deficit/Hyperactivity Disorder and Levels of Criminal Behavior among Adults. Open Journal of Social Sciences, 10(02), 1–45. https://doi.org/10.4236/jss.2022.102001

Hampton, S., Allison, C., Baron-Cohen, S., & Holt, R. (2022). Autistic People’s Perinatal Experiences I: A Survey of Pregnancy Experiences. Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-022-05754-1

Hertz-Picciotto, I., Sass, J. B., Engel, S., Bennett, D. H., Bradman, A., Eskenazi, B., Lanphear, B., & Whyatt, R. (2018). Organophosphate exposures during pregnancy and child neurodevelopment: Recommendations for essential policy reforms. PLOS Medicine, 15(10), e1002671. https://doi.org/10.1371/journal.pmed.1002671

Hoang, H. H., Tran, A. T. N., Nguyen, V. H., Nguyen, T. T. B., Nguyen, T. A. P., Le, D. D., Jatho, A., Onchonga, D., Duong, T. V., Nguyen, M. T., & Tran, B. T. (2021). Attention Deficit Hyperactivity Disorder (ADHD) and Associated Factors Among First-Year Elementary School Students. Journal of Multidisciplinary Healthcare, Volume 14, 997–1005. https://doi.org/10.2147/JMDH.S301091

Joekar, S., Amiri, S., Joekar, S., Birashk, B., & Aghebati, A. (2017). Effectiveness of a Visual Attention Training Program on the Reduction of ADHD Symptoms in Preschool Children at Risk for ADHD in Isfahan: A Pilot Study. Iranian Journal of Psychiatry and Behavioral Sciences, 11(4). https://doi.org/10.5812/ijpbs.7862

Junghänel, M., Thöne, A.-K., Ginsberg, C., Görtz-Dorten, A., Frenk, F., Mücke, K., Treier, A.-K., Labarga, S. Z., Banaschewski, T., Millenet, S., Fegert, J. M., Bernheim, D., Hanisch, C., Kölch, M., Schüller, A., Ravens-Sieberer, U., Kaman, A., Roessner, V., Hinz, J., & Döpfner, M. (2022). Irritability and Emotional Impulsivity as Core Feature of ADHD and ODD in Children. Journal of Psychopathology and Behavioral Assessment, 44(3), 679–697. https://doi.org/10.1007/s10862-022-09974-8

Karpouzas, D. G., Vryzas, Z., & Martin-Laurent, F. (2022). Pesticide soil microbial toxicity: Setting the scene for a new pesticide risk assessment for soil microorganisms (IUPAC Technical Report). Pure and Applied Chemistry, 94(10), 1161–1194. https://doi.org/10.1515/pac-2022-0201

Lee, D., Quattrocki Knight, E., Song, H., Lee, S., Pae, C., Yoo, S., & Park, H.-J. (2021). Differential structure-function network coupling in the inattentive and combined types of attention deficit hyperactivity disorder. PLOS ONE, 16(12), e0260295. https://doi.org/10.1371/journal.pone.0260295

Lopes-Ferreira, M., Maleski, A. L. A., Balan-Lima, L., Bernardo, J. T. G., Hipolito, L. M., Seni-Silva, A. C., Batista-Filho, J., Falcao, M. A. P., & Lima, C. (2022). Impact of Pesticides on Human Health in the Last Six Years in Brazil. International Journal of Environmental Research and Public Health, 19(6), 3198. https://doi.org/10.3390/ijerph19063198

Mahyuni, E. L., Harahap, U., Harahap, R. H., & Nurmaini, N. (2021). Pesticide Toxicity Prevention in Farmer’s Community Movement. Open Access Macedonian Journal of Medical Sciences, 9(E), 1–7. https://doi.org/10.3889/oamjms.2021.5565

Manley, C. K., Villanger, G. D., Thomsen, C., Cequier, E., Sakhi, A. K., Reichborn-Kjennerud, T., Herring, A. H., Øvergaard, K. R., Zeiner, P., Roell, K. R., Engel, L. S., Kamai, E. M., Thistle, J., Hall, A., Aase, H., & Engel, S. M. (2022). Prenatal Exposure to Organophosphorus Pesticides and Preschool ADHD in the Norwegian Mother, Father and Child Cohort Study. International Journal of Environmental Research and Public Health, 19(13), 8148. https://doi.org/10.3390/ijerph19138148

McDougal, E., Tai, C., Stewart, T. M., Booth, J. N., & Rhodes, S. M. (2022). Understanding and Supporting Attention Deficit Hyperactivity Disorder (ADHD) in the Primary School Classroom: Perspectives of Children with ADHD and their Teachers. Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-022-05639-3

Mioni, G., Capodieci, A., Biffi, V., Porcelli, F., & Cornoldi, C. (2019). Difficulties of children with symptoms of attention-deficit/hyperactivity disorder in processing temporal information concerning everyday life events. Journal of Experimental Child Psychology, 182, 86–101. https://doi.org/10.1016/j.jecp.2019.01.018

Mohammed, S. A., Rajashekar, S., Giri Ravindran, S., Kakarla, M., Ausaja Gambo, M., Yousri Salama, M., Haidar Ismail, N., Tavalla, P., Uppal, P., & Hamid, P. (2022). Does Vaccination Increase the Risk of Autism Spectrum Disorder? Cureus. https://doi.org/10.7759/cureus.27921

Montagna, A., Karolis, V., Batalle, D., Counsell, S., Rutherford, M., Arulkumaran, S., Happe, F., Edwards, D., & Nosarti, C. (2020). ADHD symptoms and their neurodevelopmental correlates in children born very preterm. PLOS ONE, 15(3), e0224343. https://doi.org/10.1371/journal.pone.0224343

Muna, N. R., Jatnika, R., Purwono, U., & Siregar, J. R. (2021). Differences in Attention Skills between Children with ADHD and Typically Developing Children in Indonesian Primary Schools. The Open Psychology Journal, 14(1), 329–337. https://doi.org/10.2174/1874350102114010329

Naidu, R., Biswas, B., Willett, I. R., Cribb, J., Kumar Singh, B., Paul Nathanail, C., Coulon, F., Semple, K. T., Jones, K. C., Barclay, A., & Aitken, R. J. (2021). Chemical pollution: A growing peril and potentially catastrophic risk to humanity. Environment International, 156, 106616. https://doi.org/10.1016/j.envint.2021.106616

Qian, M., Chou, S.-Y., & Lai, E. K. (2020). Confirmatory bias in health decisions: Evidence from the MMR-autism controversy. Journal of Health Economics, 70, 102284. https://doi.org/10.1016/j.jhealeco.2019.102284

Qin, X., Li, P., Wu, Y., Wang, X., Yan, S., Xu, Y., Zhu, P., Hao, J., Tao, F., & Huang, K. (2022). Impact of cesarean delivery on children’s autism-like behaviors: The mediation of exclusive breastfeeding. International Breastfeeding Journal, 17(1), 53. https://doi.org/10.1186/s13006-022-00493-6

Ra, C. K., Cho, J., Stone, M. D., De La Cerda, J., Goldenson, N. I., Moroney, E., Tung, I., Lee, S. S., & Leventhal, A. M. (2018). Association of Digital Media Use With Subsequent Symptoms of Attention-Deficit/Hyperactivity Disorder Among Adolescents. JAMA, 320(3), 255. https://doi.org/10.1001/jama.2018.8931

Raffa, C. M., & Chiampo, F. (2021). Bioremediation of Agricultural Soils Polluted with Pesticides: A Review. Bioengineering, 8(7), 92. https://doi.org/10.3390/bioengineering8070092

Rahman, D. A., Zakianis, Z., & Fitria, L. (2015). Pesticide Exposure, Behavior of Farmer, and Activity of Cholinesterase Enzyme in Blood of Fertile Women Farmers. Kesmas: National Public Health Journal, 10(2), 51. https://doi.org/10.21109/kesmas.v10i2.879

Rajaram, K. (2023). How do heavy metals cause and impact Autism [Preprint] https://doi.org/10.14293/S2199-1006.1.SOR-.PPA0SNG.v1

Rani, L., Thapa, K., Kanojia, N., Sharma, N., Singh, S., Grewal, A. S., Srivastav, A. L., & Kaushal, J. (2021). An extensive review of the consequences of chemical pesticides on human health and the environment. Journal of Cleaner Production, 283, 124657. https://doi.org/10.1016/j.jclepro.2020.124657

Riyaz, M., Ahmad Shah, R., & Sivasankaran, K. (2022). Pesticide Residues: Impacts on Fauna and the Environment. In K. Ferreira Mendes, R. Nogueira De Sousa, & K. Cabral Mielke (Eds.), Biodegradation Technology of Organic and Inorganic Pollutants. IntechOpen. https://doi.org/10.5772/intechopen.98379

Sabran, S. H., & Abas, A. (2021). Knowledge and Awareness on the Risks of Pesticide Use Among Farmers at Pulau Pinang, Malaysia. SAGE Open, 11(4), 215824402110648. https://doi.org/10.1177/21582440211064894

Saiz-Rubio, V., & Rovira-Más, F. (2020). From Smart Farming towards Agriculture 5.0: A Review on Crop Data Management. Agronomy, 10(2), 207. https://doi.org/10.3390/agronomy10020207

Salari, N., Ghasemi, H., Abdoli, N., Rahmani, A., Shiri, M. H., Hashemian, A. H., Akbari, H., & Mohammadi, M. (2023). The global prevalence of ADHD in children and adolescents: A systematic review and meta-analysis. Italian Journal of Pediatrics, 49(1), 48. https://doi.org/10.1186/s13052-023-01456-1

Sharma, A., Kumar, V., Shahzad, B., Tanveer, M., Sidhu, G. P. S., Handa, N., Kohli, S. K., Yadav, P., Bali, A. S., Parihar, R. D., Dar, O. I., Singh, K., Jasrotia, S., Bakshi, P., Ramakrishnan, M., Kumar, S., Bhardwaj, R., & Thukral, A. K. (2019). Worldwide pesticide usage and its impacts on the ecosystem. SN Applied Sciences, 1(11), 1446. https://doi.org/10.1007/s42452-019-1485-1

Silk, T. J., Malpas, C. B., Beare, R., Efron, D., Anderson, V., Hazell, P., Jongeling, B., Nicholson, J. M., & Sciberras, E. (2019). A network analysis approach to ADHD symptoms: More than the sum of its parts. PLOS ONE, 14(1), e0211053. https://doi.org/10.1371/journal.pone.0211053

Singh, S., Sharma, P., Pal, N., Kumawat, M., Shubham, S., Sarma, D. K., Tiwari, R. R., Kumar, M., & Nagpal, R. (2022). Impact of Environmental Pollutants on Gut Microbiome and Mental Health via the Gut–Brain Axis. Microorganisms, 10(7), 1457. https://doi.org/10.3390/microorganisms10071457

Slobodin, O., & Davidovitch, M. (2019). Gender Differences in Objective and Subjective Measures of ADHD Among Clinic-Referred Children. Frontiers in Human Neuroscience, 13, 441. https://doi.org/10.3389/fnhum.2019.00441

Solanto, M. V. (2000). The Predominantly Inattentive Subtype of Attention-Deficit/Hyperactivity Disorder. CNS Spectrums, 5(6), 45–51. https://doi.org/10.1017/S1092852900007069

Thistle, J. E., Ramos, A., Roell, K. R., Choi, G., Manley, C. K., Hall, A. M., Villanger, G. D., Cequier, E., Sakhi, A. K., Thomsen, C., Zeiner, P., Reichborn-Kjennerud, T., Øvergaard, K. R., Herring, A., Aase, H., & Engel, S. M. (2022). Prenatal organophosphorus pesticide exposure and executive function in preschool-aged children in the Norwegian Mother, Father and Child Cohort Study (MoBa). Environmental Research, 212, 113555. https://doi.org/10.1016/j.envres.2022.113555

Thompson, K. N., Agnew-Blais, J. C., Allegrini, A. G., Bryan, B. T., Danese, A., Odgers, C. L., Matthews, T., & Arseneault, L. (2023). Do Children with Attention-Deficit/Hyperactivity Disorder Symptoms Become Socially Isolated? Longitudinal Within-Person Associations in a Nationally Representative Cohort. JAACAP Open, 1(1), 12–23. https://doi.org/10.1016/j.jaacop.2023.02.001

Van Hoorn, J., De Water, E., Dekkers, T. J., Pollak, Y., Popma, A., Jansen, B. R. J., Huizenga, H. M., & Van Duijvenvoorde, A. C. K. (2022). Peer feedback decreases impulsive choice in adolescents with and without attention deficit/hyperactivity disorder. JCPP Advances, 2(1). https://doi.org/10.1002/jcv2.12065

Von Ehrenstein, O. S., Ling, C., Cui, X., Cockburn, M., Park, A. S., Yu, F., Wu, J., & Ritz, B. (2019). Prenatal and infant exposure to ambient pesticides and autism spectrum disorder in children: Population-based case-control study. BMJ, l962. https://doi.org/10.1136/bmj.l962

Werheni Ammeri, R., Hidri, Y., & Abdenaceur, H. (2021). Effect of PCP Pesticide Contamination on Soil Quality. In M. L. Larramendy & S. Soloneski (Eds.), Soil Contamination-Threats and Sustainable Solutions. IntechOpen. https://doi.org/10.5772/intechopen.93714

Widianto, E. P., Arista Maisyaroh, & Rizeki Dwi Fibriansari. (2019). Proactive Public Health Approach to Prevention of Occupational Disease On Farmers In Lumajang. https://doi.org/10.5281/ZENODO.3365519

Zhang, L., Yan, C., Guo, Q., Zhang, J., & Ruiz-Menjivar, J. (2018). The impact of agricultural chemical inputs on the environment: Global evidence from informetrics analysis and visualization. International Journal of Low-Carbon Technologies. https://doi.org/10.1093/ijlct/cty039

Author Biographies

Friska Eka Fitria, Universitas Andalas and Sekolah Tinggi Ilmu Kesehatan Indonesia

Doctoral Programme of Public Health, Faculty of Medicine and Department of Occupational Health and Safety

Nur Afrainin Syah, Universitas Andalas

Department Of Medical Education, Faculty of Medicine

Jamsari, Universitas Andalas

Department of Genomic and Molecular Breeding, Faculty of Agriculture

Yuniar Lestari, Universitas Andalas

Department of Public Health, Faculty of Medicine

License

Copyright (c) 2023 Friska Eka Fitria, Nur Afrainin Syah, Jamsari, Yuniar Lestari

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with Jurnal Penelitian Pendidikan IPA, agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, web sites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Jurnal Penelitian Pendidikan IPA.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).