Development of Optical Sensor Technology for Non-Invasive Hemoglobin Measurement

Authors

Muthmainnah , Fabriansyah Zakaria Arabani , Imam Tazi , Ninik Chamidah , Wiwis Sasmitaninghidayah , Mokhamad Tirono

DOI:

10.29303/jppipa.v9i11.5610

Published:

2023-11-25

Issue:

Vol. 9 No. 11 (2023): November

Keywords:

Calibration, Hemoglobin, Non-Invasive, Optical Sensor

Research Articles

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How to Cite

Muthmainnah, Arabani, F. Z. ., Tazi, I. ., Chamidah, N. ., Sasmitaninghidayah, W. ., & Tirono, M. . (2023). Development of Optical Sensor Technology for Non-Invasive Hemoglobin Measurement . Jurnal Penelitian Pendidikan IPA, 9(11), 10252–10258. https://doi.org/10.29303/jppipa.v9i11.5610

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Abstract

This research focuses on the development of hardware and software required to implement optical sensor technology. The optical sensor used is the MAX30102, equipped with infrared (IR) and red-light sources along with a receiver. The signals generated by the sensor are processed by NodeMCU and displayed on the OLED. The calibration results indicate the relationship between hemoglobin obtained using the invasive method and the output of the MAX30102 sensor, which is in the form of wavelength. It has the equation  with an  value of 0.9114. This equation is utilized to program the NodeMCU through the Arduino IDE. Validation and clinical trials have been conducted to evaluate its accuracy and applicability in clinical contexts. The results show that the non-invasive device has an average standard deviation of 0.32, indicating consistent measurement values. The non-invasive device demonstrates an average accuracy of 99.24%, signifying high precision and similarity to invasive methods. This suggests that the device holds potential as an innovative solution for Hemoglobin measurement.

References

Adegoke, S. A., Oladimeji, O. I., Akinlosotu, M. A., Akinwumi, A. I., & Matthew, K. A. (2022). HemoTypeSC point-of-care testing shows high sensitivity with alkaline cellulose acetate hemoglobin electrophoresis for screening hemoglobin SS and SC genotypes. Hematology, Transfusion and Cell Therapy, 44(3), 341–345. https://doi.org/10.1016/j.htct.2020.11.010

Akinbosede, D., Chizea, R., & Hare, S. A. (2022). Pirates of the haemoglobin. Microbial Cell, 9(4), 84–102. https://doi.org/10.15698/MIC2022.04.775

Chambouleyron, V., Fauvarque, O., Sauvage, J. F., Dohlen, K., Levraud, N., Vigan, A., N’diaye, M., Neichel, B., & Fusco, T. (2021). Variation on a Zernike wavefront sensor theme: Optimal use of photons. Astronomy and Astrophysics, 650, 1–7. https://doi.org/10.1051/0004-6361/202140870

Chen, W. L., Nishita, Y., Nakamura, A., Kato, T., Nakagawa, T., Zhang, S., Shimokata, H., Otsuka, R., Su, K. P., & Arai, H. (2022). Hemoglobin concentration is associated with the hippocampal volume in community-dwelling adults. Archives of Gerontology and Geriatrics, 101, 104668. https://doi.org/10.1016/j.archger.2022.104668

Dervieux, E., Bodinier, Q., Uhring, W., & Théron, M. (2020). Measuring hemoglobin spectra: searching for carbamino-hemoglobin. Journal of Biomedical Optics, 25(10), 1050011–1050026. https://doi.org/10.1117/1.jbo.25.10.105001

Dhruba, A. R., Alam, K. N., Khan, M. S., Bourouis, S., & Khan, M. M. (2021). Development of an IoT-Based Sleep Apnea Monitoring System for Healthcare Applications. Computational and Mathematical Methods in Medicine, 2021, 1-16. https://doi.org/10.1155/2021/7152576

Diharja, R., Fahlevi, M. R., Rahayu, E. S., & Handini, W. (2022). Prototype-Design of Soil Movement Detector Using IoT Hands-on Application. Jurnal Penelitian Pendidikan IPA, 8(4), 2245–2254. https://doi.org/10.29303/jppipa.v8i4.1709

Farook, M. A. A., Rukmanidevi, S., & Shanker, N. R. (2023). Haemoglobin Measurement from Eye Anterior Ciliary Arteries through Borescope Camera. Computer Systems Science and Engineering, 44(2), 1763–1774. https://doi.org/10.32604/csse.2023.026260

Garrett B, J., Jeanette M, P., Michael D, S., Charles E, W., John B, H., & Laura J, M. (2021). Evaluation of Noninvasive Hemoglobin Measurements in Trauma Patients: A Repeat Study. Journal of Surgical Research, 266, 213–221. https://doi.org/10.1016/j.jss.2021.04.015

Gonnade, N., Bajpayee, A., Elhence, A., Lokhande, V., Mehta, N., & Mishra, M. (2017). and using cord blood for transfusion Azikiwe University Teaching Hospital. 12(2), 105–111. https://doi.org/10.4103/ajts.AJTS

Hasan, M. K., Aziz, M. H., Zarif, M. I. I., Hasan, M., Hashem, M. M. A., Guha, S., Love, R. R., & Ahamed, S. (2021). Noninvasive hemoglobin level prediction in a mobile phone environment: State of the art review and recommendations. JMIR MHealth and UHealth, 9(4). https://doi.org/10.2196/16806

Hidayat, N., & Yulianti, E. (2021). Real Time Measurement for Spring-Mass System: The Graphical and Mathematical Representations. Jurnal Penelitian Pendidikan IPA, 7(1), 74. https://doi.org/10.29303/jppipa.v7i1.458

Holovatyy, A., Teslyuk, V., Kryvinska, N., & Kazarian, A. (2020). Development of microcontroller-based system for background radiation monitoring. Sensors (Switzerland), 20(24), 1–14. https://doi.org/10.3390/s20247322

Hong, W. J., Shamsuddin, N., Abas, E., Apong, R. A., Masri, Z., Suhaimi, H., Gödeke, S. H., & Noh, M. N. A. (2021). Water quality monitoring with arduino based sensors. Environments - MDPI, 8(1), 1–15. https://doi.org/10.3390/environments8010006

Hsu, D. P., French, A. J., Madson, S. L., Palmer, J. M., & Gidvani-Diaz, V. (2016). Evaluation of a Noninvasive Hemoglobin Measurement Device to Screen for Anemia in Infancy. Maternal and Child Health Journal, 20(4), 827–832. https://doi.org/10.1007/s10995-015-1913-9

Hudhajanto, R. P., Mulyadi, I. H., & Sandi, A. A. (2022). Wearable Sensor Device berbasis IoT berbentuk Face Shield untuk Memonitor Detak Jantung. Jurnal of Applied Informatics and Computing (JAIC), 6(1), 87–92. https://doi.org/10.30871/jaic.v6i1.4105

Kemalasari, & Rochmad, M. (2022). Deteksi Kadar Saturasi Oksigen Darah (Spo2) Dan Detak Jantung Secara Non-Invasif Dengan Sensor Chip MAX30100. Jurnal Nasional Teknologi Terapan (JNTT), 4(1), 35–50. https://doi.org/10.22146/jntt.v4i1.4804

Khan, M. M., Mehnaz, S., Shaha, A., Nayem, M., & Bourouis, S. (2021). IoT-Based Smart Health Monitoring System for COVID-19 Patients. Computational and Mathematical Methods in Medicine, 2021. https://doi.org/10.1155/2021/8591036

Lafifa, F., & Rosana, D. (2023). Development and Validation of Animation-Based Science Learning Media in the STEM-PBL Model to Improve Students Critical Thinking and Digital Literacy. Jurnal Penelitian Pendidikan IPA, 9(9), 7445–7453. https://doi.org/10.29303/jppipa.v9i9.4448

Lamhaut, L., Apriotesei, R., Combes, X., Lejay, M., Carli, P., & Vivien, B. (2011). Comparison of the accuracy of noninvasive hemoglobin monitoring by spectrophotometry (SpHb) and hemocue® with automated laboratory hemoglobin measurement. Anesthesiology, 115(3), 548–554. https://doi.org/10.1097/ALN.0b013e3182270c22

Lensoni, L., Karma, T., & Wilianda, I. (2023). Effect of Bamboo Charcoal on pH and Hardware in Dailed Well Water. Jurnal Penelitian Pendidikan IPA, 9(3), 1129–1134. https://doi.org/10.29303/jppipa.v9i3.3350

Man, J., Zielinski, M. D., Das, D., Wutthisirisart, P., & Pasupathy, K. S. (2022). Improving non-invasive hemoglobin measurement accuracy using nonparametric models. Journal of Biomedical Informatics, 126, 103975. https://doi.org/10.1016/j.jbi.2021.103975

Murti, S., Megantoro, P., De Brito Silva, G., & Maseleno, A. (2020). Design and analysis of DC electrical voltage-current data logger device implemented on wind turbine control system. Journal of Robotics and Control (JRC), 1(3), 75–80. https://doi.org/10.18196/jrc.1317

Muthmainnah, M., Tabriawan, D. B., D., Maulana, U., & Ibrahim, M. (2022). Prototipe Alat Ukur Detak Jantung Menggunakan Sensor MAX30102 Berbasis Internet of Things (IoT) ESP8266 dan Blynk. In Jurnal Informatika Sunan Kalijaga), 7(3). https://doi.org/10.14421/jiska.2022.7.3.163-176

Pinto, C., Parab, J., & Naik, G. (2020). Non-invasive hemoglobin measurement using embedded platform. Sensing and Bio-Sensing Research, 29, 100370. https://doi.org/10.1016/j.sbsr.2020.100370

Prasetyo, H., Sari, F. N. I., Hidayati, R. N., & Apriyanto, R. L. (2021). Portable urine alcohol detector fabrication with arduino microcontroller-based MQ-3 sensor. Gravity : Jurnal Ilmiah Penelitian Dan Pembelajaran Fisika, 7(2), 38–45. https://doi.org/10.30870/gravity.v7i2.11376

Pratama, R. A., Bangsa, I. A., & Rahmadewi, R. (2020). Implementasi Sensor Detak Jantung MAX30100 dan Sensor Konduktansi Kulit GSR menggunakan Mikrokontroller Arduino Pada Alat Pendeteksi Tingkat Stress. Jurnal Ilmiah Wahana Pendidikan, 6(3), 295–307. https://doi.org/10.5281/zenodo.4541288

Rahmat, H. H., & Ambaransari, D. R. (2018). Sistem Perekam Detak Jantung Berbasis Pulse Heart Rate Sensor pada Jari Tangan. ELKOMIKA: Jurnal Teknik Energi Elektrik, Teknik Telekomunikasi, & Teknik Elektronika, 6(3), 344. https://doi.org/10.26760/elkomika.v6i3.344

Ramesh, S., Biswas, S., Sarmah, S., Karmakar, S., & Das, P. (2021). A Working Prototype Using DS18B20 Temperature Sensor and Arduino for Health Monitoring. SN Computer Science, 2(1), 1–21. https://doi.org/10.1007/s42979-020-00434-2

Resika, A. , I. K., Pradnyana, I. M. A., & Kurniati, D. P. Y. (2018). Sistem Monitoring Detak Jantung dan Lokasi Pasien. Jurnal Pendidikan Teknologi Dan Kejuruan, 15(1), 124–133. https://doi.org/10.23887/jptk-undiksha.v15i1.13115

Ryan, M. L., Maxwell, A. C., Manning, L., Jacobs, J. D., Bachier-Rodriguez, M., Feliz, A., & Williams, R. F. (2016). Noninvasive hemoglobin measurement in pediatric trauma patients. Journal of Trauma and Acute Care Surgery, 81(6), 1162–1166. https://doi.org/10.1097/TA.0000000000001160

Shangguan, Q., Chen, Z., Yang, H., Cheng, S., Yang, W., Yi, Z., Wu, X., Wang, S., Yi, Y., & Wu, P. (2022). Design of Ultra-Narrow Band Graphene Refractive Index Sensor. Sensors, 22(17), 1–13. https://doi.org/10.3390/s22176483

Taneri, P. E., Gómez-Ochoa, S. A., Llanaj, E., Raguindin, P. F., Rojas, L. Z., Roa-Díaz, Z. M., Salvador, D., Groothof, D., Minder, B., Kopp-Heim, D., Hautz, W. E., Eisenga, M. F., Franco, O. H., Glisic, M., & Muka, T. (2020). Anemia and iron metabolism in COVID-19: a systematic review and meta-analysis. European Journal of Epidemiology, 35(8), 763–773. https://doi.org/10.1007/s10654-020-00678-5

Whitehead, R. D., Mei, Z., Mapango, C., & Jefferds, M. E. D. (2019). Methods and analyzers for hemoglobin measurement in clinical laboratories and field settings. Annals of the New York Academy of Sciences, 1450(1), 147–171. https://doi.org/10.1111/nyas.14124

Wittenmeier, E., Paumen, Y., Mildenberger, P., Smetiprach, J., Pirlich, N., Griemert, E. V., Kriege, M., & Engelhard, K. (2021). Non-invasive haemoglobin measurement as an index test to detect pre-operative anaemia in elective surgery patients – a prospective study. Anaesthesia, 76(5), 647–654. https://doi.org/10.1111/anae.15312

Yuhefizar, Y., Nasution, A., Putra, R., Asri, E., & Satria, D. (2019). Alat Monitoring Detak Jantung Untuk Pasien Beresiko Berbasis IoT Memanfaatkan Aplikasi OpenSID berbasis Web. Jurnal RESTI (Rekayasa Sistem Dan Teknologi Informasi), 3(2), 265–270. https://doi.org/10.29207/resti.v3i2.974

Author Biographies

Muthmainnah, Universitas Islam Negeri Maulana Malik Ibrahim Malang

Fabriansyah Zakaria Arabani, Universitas Islam Negeri Maulana Malik Ibrahim Malang, Malang

Imam Tazi, Universitas Islam Negeri Maulana Malik Ibrahim Malang, Malang

Ninik Chamidah, Universitas Islam Negeri Maulana Malik Ibrahim Malang, Malang

Wiwis Sasmitaninghidayah, Universitas Islam Negeri Maulana Malik Ibrahim Malang, Malang

Mokhamad Tirono, Universitas Islam Negeri Maulana Malik Ibrahim Malang, Malang

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Copyright (c) 2023 Muthmainnah, Fabriansyah Zakaria Arabani, Imam Tazi, Ninik Chamidah, Wiwis Sasmitaninghidayah, Mokhamad Tirono

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