The Use of Green Tea Extract (Camellia sinensis) Orally to Prevent Dyslipidemia in Female Rats (Rattus norvegicus) Fed A High-Fat Diet

Authors

Christina J. R. Esmaralda Lumbantobing , Risna Damayanti , Liena

DOI:

10.29303/jppipa.v9i12.6520

Published:

2023-12-20

Issue:

Vol. 9 No. 12 (2023): December

Keywords:

Cholesterol, Dyslipidemia, Green tea, High-fat

Research Articles

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How to Cite

Lumbantobing, C. J. R. E. ., Damayanti, R. ., & Liena. (2023). The Use of Green Tea Extract (Camellia sinensis) Orally to Prevent Dyslipidemia in Female Rats (Rattus norvegicus) Fed A High-Fat Diet. Jurnal Penelitian Pendidikan IPA, 9(12), 11862–11870. https://doi.org/10.29303/jppipa.v9i12.6520

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Abstract

One of the significant danger factors for cardiovascular disease and stroke is dyslipidemia. According to long-term prospective epidemiological research, coronary heart disease is less common in those with good lipid profiles who lead better lives. In this study, on a high-fat diet, female wistar rats (Rattus norvegicus) will be tested and analyzed to see if green tea extract (Camellia sinensis) can prevent dyslipidemia when given orally. Compared to a control group that received only distilled water, the trial group that received 5 milliliters of green tea extract (Camellia sinensis) had significantly lower total and LDL cholesterol levels and higher HDL cholesterol levels. This treatment was more effective in lowering cholesterol overall. The components found in green tea (Camellia sinensis), including tannins, steroids, alkaloids, saponins, and flavonoids, can induce this. When certain bioactive substances are off, the body can bring them back into normalcy. These results suggest that white wistar rats (Rattus norvegicus), given a high-fat diet, can benefit from green tea (Camellia sinensis) extract to avoid dyslipidemia. Your lipid profile can be improved by ingesting green tea extract. The primary polyphenol in tea, catechin, is responsible for this transformation. Therefore, the Camellia sinensis plant, from which green tea is made, is a valuable plant that can halt or slow the progression of several ailments, including hypertension, metabolic disorders, and cardiovascular disorders.

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Author Biographies

Christina J. R. Esmaralda Lumbantobing, Faculty of Medicine, Dentistry and Health Sciences, Prima Indonesia University, Medan, Indonesia

Risna Damayanti, Faculty of Medicine, Dentistry and Health Sciences, Prima Indonesia University, Medan, Indonesia

Liena, Faculty of Medicine, Dentistry and Health Sciences, Prima Indonesia University, Medan, Indonesia

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Copyright (c) 2023 Christina J. R. Esmaralda Lumbantobing, Risna Damayanti, Liena

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