Vol. 9 No. 12 (2023): December
Open Access
Peer Reviewed

Comparison of Serum Glutamic Pyruvic Transaminase and Serum Glutamic Oxaloacetic Transaminase Enzyme Levels between Light and Heavy Drinkers in Renon Village, Denpasar City

Authors

Ni Putu Rahayu Artini , I Wayan Tanjung Aryasa

DOI:

10.29303/jppipa.v9i12.6612

Published:

2023-12-20

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Abstract

Arak is a non-electrolyte liquid that easily circulates in the blood circulation and is absorbed in the digestive tract. One disease that can be caused by alcohol consumption is liver function disorders, such as alcoholic hepatitis. So it can increase the serum enzymes glutamate pyruvate transaminase (SGPT) and serum glutamic oxaloacetic transaminase (SGOT). This research was conducted on light and heavy drinkers in Renon Village, Denpasar City. This research uses a longitudinal quantitative design. The results obtained were that the average SGPT level of light drinkers was 46.21 ± 0.155 IU/L, while the respondents who were heavy drinkers had SGPT levels with an average of 64.02 ± 0.430 IU/L. for SGOT from light drinkers is 50.20 ± 0.101 IU/L. Respondents who drank heavily had SGPT levels with an average of 74.40 ± 0.048 IU/L. All wine drinkers, both light drinkers and heavy drinkers, had SGPT-SGOT levels that exceeded the reference value.

Keywords:

Arak Heavy drinkers Light drinkers SGOT SGPT

References

Amirudin, R. (2009). Buku Ilmu Penyakit dalam: Fisiologi dan Biokimia Hati. Edisi V. Jakarta: Interna Publishing.

Andayani, A. A. I., Martono, E., & Muhamad, M. (2017). Pemberdayaan Masyarakat Melalui Pengembangan Desa Wisata dan Implikasinya terhadap Ketahanan Sosial Budaya Wilayah (Studi di Desa Wisata Penglipuran Bali). Jurnal Ketahanan Nasional, 23(1), 1. https://doi.org/10.22146/jkn.18006

Aritonang, I. (2012). Penyelenggaraan Makanan. Yogyakarta: Jurusan Gizi Poltekkes.

Astuti, N. P. W., Suaniti, N. M., & Mustika, I. G. (2018). Validasi Metode dalam Penentuan Kadar Etanol pada Arak Menggunakan Kromatografi Gas Detektor Ionisasi Nyala. Jurnal Kimia (Journal of Chemistry), 12(2), 128-133. https://doi.org/10.24843/JCHEM.2018.v12.i02.p06

Bidlabfor Polda Bali. (2019). Instruksi Kerja Laboratorium Forensik Cabang Denpasar-Bali. Retrieved from https://bidlabfor.bali.polri.go.id/

Conreng, D., Waleleng, B. J., & Palar, S. (2014). Hubungan Konsumsi Alkohol dengan Gangguan Fungsi Hati pada Subjek Pria Dewasa Muda di Kelurahan Tateli dan Teling Atas Manado. Jurnal E-Clinic (eCl), 2(2), 35-46. https://doi.org/10.35790/ecl.v2i2.5026

DiaSys, D. (2020). Clinical Chemistry SGPT, DiaSys Diagnostic Systems GmbH. Germany. Retrieved from https://www.diasys-diagnostics.com/products/reagents/clinical-chemistry/

Dorland, W. N. (2008). Kamus Saku Kedokteran Dorland (28 ed.). (Hartanto, Y. B., Nirmala, W. K., Ardy, A., & Setiono, S. Eds.) Jakarta: Elsevier.

Farha, R. A., & Eman, A. (2018). Shift Work and the Risk of Cardiovascular Diseases and Metabolic Syndrome among Jordanian Employees. Oman Medical Journal, 33(3), 235-242. https://doi.org/10.5001/omj.2018.43

Frayekti, M. (2013). Makalah Kromatografi Gas. Jakarta: Program Studi Teknik Pengolahan Gas PT Badak NGL LNG Academy Jakarta.

Gadallah, M., Hakmi, S., Eldin, W. S., & Mohsen, A. (2017). Association of Rotating Night Shift with Lipid Profile among Nurses in an Egyptian Tertiary University Hospital. Eastern Mediterranean Health Journal, 23(4), 295-307. https://doi.org/10.26719/2017.23.4.295

Gandasoebrata, R. (2011). Penuntun Laboratorium Klinik. Jakarta: Dian Rakyat.

Ghelichpour, M., Mirghaed, A. T., Hoseini, S. M., & Jimenez, A. P. (2020). Plasma Antioxidant and Hepatic Enzymes Activity, Thyroid Hormones Alterations and Health Status of Liver Tissue in Common Carp (Cyprinus carpio) Exposed to Lufenuron. Aquaculture, 516, 734634. https://doi.org/10.1016/j.aquaculture.2019.734634

Glory, C., Arthur, A., & Hall, E. J. (2020). Buku Ajar Fisiologi Kedokteran. Jakarta: Gramedia.

Indrayani, A. A. S. M., Artini, N. P. R., & Aryasa, I. W. T. (2019). Analisis Kadar Trigliserida dan HDL (High Density Lipoprotein) pada Tenaga Farmasi di Apotek Indobat Denpasar. The Journal of Muhammadiyah Medical Laboratory Technologist, 2(2), 18-27. https://doi.org/10.30651/jmlt.v2i2.2581

Jawi, M., Suprapta, D. M., & Sutirtayasa, W. P. (2007). Efek Antioksidan Ekstrak Umbi Ubi Jalar Ungu (Ipomoiea batatas L) terhadap Hati setelah Aktivitas Fisik Maksimal dengan Melihat Kadar AST dan ALT Darah pada Mencit. Dexa Media, 20(3), 65-71.

Julia, S. R. (2016). Efek Minuman Keras Oplosan terhadap Perubahan Histopatologi Lambung Tikus Wistar Jantan (Undergraduate thesis). Fakultas Kedokteran Universitas Jember, Jember. Retrieved from https://repository.unej.ac.id/handle/123456789/73581

Kahar, H. (2018). Pengaruh Hemolisis terhadap Kadar Serum Glutamate Pyruvate Transaminase (SGPT) sebagai Salah Satu Parameter Fungsi Hati. The Journal of Muhammadiyah Medical Laboratory Technologist, 1(1), 45-53. https://doi.org/10.30651/jmlt.v1i1.981

Logan, B. K., Case, G. A., & Distefano, S. (1999). Alcohol Content of Beer and Malt Beverages: Forensic Considerations. J Forensic Sci., 44(6), 1292-1295. Retrieved from https://pubmed.ncbi.nlm.nih.gov/10744486/

Muna, E. D. M., Bizarri, C. H. B., Maciel, J. R. M., Rocha, G. P., & Araujo, I. O. (2015). Method Validation for Methanol Quantification Present in Working Places. Journal of Physics Conference Series, 575(1), 012031. https://doi.org/10.1088/1742-6596/575/1/012031

Ortega, C., López, R., Cacho, J., & Ferreira, V. (2001). Fast Analysis of Important Wine Volatile Compounds Development and Validation of a New Method Based on Gas Chromatographic–Flame Ionisation Detection Analysis of Dichloromethane Microextracts. Journal of Chromatography A, 923(1-2), 205–214. https://doi.org/10.1016/S0021-9673(01)00972-4

Paasma, R., Hovda, K. E., & Jacobsen, D. (2009). Methanol Poisoning and Long Term Sequelae–a Six Years Follow-up after a Large Methanol Outbreak. BMC Clinical Pharmacology, 9(5). https://doi.org/10.1186/1472-6904-9-5

Pearce, E. C. (2009). Anatomi dan Fisiologi untuk Paramedic. Jakarta: PT Gramedia Pustaka Umum.

PERPRES. (2013). Peraturan Presiden Republik Indonesia Nomor 74 Tahun 2013 tentang Pengendalian dan Pengawasan Minuman Beralkohol. Jakarta: Kemensekneg.

Pizarro, C., Sáenz-González, C., Pérez-del-Notario, N., & González-Sáiz J. M. (2011). Development of a Dispersive LiquidLiquid Microextraction Method for the Simultaneous Determination of the Main Compounds Causing Cork Taint and Brett Character in Wines Using Gas Chromatography-Tandem Mass Spectometry. Journal of Chromatography A, 1218(12), 1576-1584. https://doi.org/10.1016/j.chroma.2011.01.055

Pospos N. (2002). Alkohol Merusak Sel Hati dan Pengaruhnya terhadap Konsentrasi ATP Intraseluler. Jakarta: Widya Medika.

Rini, H. S. (2012). Prilaku Kriminal pada Pecandu Alkohol. Depok: Fakultas Psikologi Universitas Gunadarma.

Riyanto, R. (2014). Validasi & Verifikasi Metode Uji: Sesuai dengan ISO/IEC 17025 Laboratorium Pengujian dan Kalibrasi. Yogyakarta: Deepublish.

Sarja, N. L. A. K. Y., Widana, I. P. K. A., Suprapto, P. A., & Pamularsih, T. R. (2021). Developing Green Tourism-Based Model of Information Technology Utilization in Tourism Villages. International Journal of Applied Sciences in Tourism and Events, 5(2), 153-165. http://dx.doi.org/10.31940/ijaste.v5i2.153-165

Suaniti, N. M., Asih, I. A. R. A., & Astuti, N. P. W. (2012). Deteksi Etanol Setelah Konsumsi Arak dalam Urin dengan Gas Chromatography. Jurnal Kimia (Journal of Chemistry), 6(2), 123-124. Retrieved from https://ojs.unud.ac.id/index.php/jchem/article/view/5951

Author Biographies

Ni Putu Rahayu Artini, Program Studi Teknologi Laboratorium Medik, Fakultas Ilmu-Ilmu Kesehatan, Universitas Bali Internasional, Denpasar, Indonesia

Author Origin : Indonesia

I Wayan Tanjung Aryasa, Program Studi Teknologi Laboratorium Medik, Fakultas Ilmu-Ilmu Kesehatan, Universitas Bali Internasional, Denpasar, Indonesia

Author Origin : Indonesia

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How to Cite

Artini, N. P. R. ., & Aryasa, I. W. T. . (2023). Comparison of Serum Glutamic Pyruvic Transaminase and Serum Glutamic Oxaloacetic Transaminase Enzyme Levels between Light and Heavy Drinkers in Renon Village, Denpasar City. Jurnal Penelitian Pendidikan IPA, 9(12), 11871–11876. https://doi.org/10.29303/jppipa.v9i12.6612