Characterization of Bioactive Compounds and Stability of Mangrove Extract Rhizopora Sp.

Authors

Dirk Y. P. Runtuboi , Ervina Indrayani , Imam Mishbach , Gabriela Olivia Karisoh

DOI:

10.29303/jppipa.v10i10.8674

Published:

2024-10-25

Issue:

Vol. 10 No. 10 (2024): October

Keywords:

Bioactive compounds, Characterization, Mangrove extracts of rhizopora Sp., Stability

Research Articles

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Runtuboi, D. Y. P., Indrayani, E., Mishbach, I., & Karisoh, G. O. (2024). Characterization of Bioactive Compounds and Stability of Mangrove Extract Rhizopora Sp. Jurnal Penelitian Pendidikan IPA, 10(10), 7447–7455. https://doi.org/10.29303/jppipa.v10i10.8674
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Abstract

In recent decades, bioactive compounds contained in plants have increasingly attracted the attention of researchers. This is because these bioactive compounds have the potential to be used as raw materials in the manufacture of health products, medicines, and cosmetics. However, in developing products based on bioactive compounds in Rhizopora sp. mangroves, sufficient knowledge about these compounds is needed. The main objective of this study was to identify bioactive compounds and evaluate the stability of Rhizopora sp. mangrove extract obtained from Youtefa Bay area, Jayapura City. The methods used include mangrove leaf sampling, maceration extraction using methanol, followed by fractionation and phytochemical tests to detect the content of active compounds. Data analysis was performed using UV and IR spectroscopy. The results showed that the isolated Rhizophora sp. mangrove leaf extract obtained from Youtefa Bay waters contained several bioactive compound activities such as alkaloid, flavonoid, phenolic, and saponin bioactive compound groups in methanol solvents.  In conclusion, mangrove Rhizophora sp. from Youtefa Bay has great potential as a source of bioactive compounds that can be further developed in various commercial products.

References

Asworo, R. Y., & Widwiastuti, H. (2023). Pengaruh Ukuran Serbuk Simplisia dan Waktu Maserasi terhadap Aktivitas Antioksidan Ekstrak Kulit Sirsak. Indonesian Journal of Pharmaceutical Education, 3(2). https://doi.org/10.37311/ijpe.v3i2.19906

Bergonzi, M. C., Heard, C. M., & Garcia-Pardo, J. (2022). Bioactive molecules from plants: discovery and pharmaceutical applications. Pharmaceutics, 14(10), 2116. https://doi.org/10.3390/pharmaceutics14102116

Cerri, F., Giustra, M., Anadol, Y., Tomaino, G., Galli, P., Labra, M., & Colombo, M. (2022). Natural products from mangroves: an overview of the anticancer potential of Avicennia marina. Pharmaceutics, 14(12), 2793. https://doi.org/10.3390/pharmaceutics14122793

Chaachouay, N., & Zidane, L. (2024). Plant-derived natural products: a source for drug discovery and development. Drugs and Drug Candidates, 3(1), 184–207. https://doi.org/10.3390/ddc3010011

Dwijayanti, E., Zoraida, M. N., & Kurnianingsih, S. R. (2023). Antioxidant Activity Testing Combination of Moringa Leaf (Moringa oleifera L.) and Bambian (Ocimum sanctum L.) Leaves Extract Using DPPH Method. Stannum: Jurnal Sains Dan Terapan Kimia, 5(1), 43–50. https://doi.org/10.33019/jstk.v5i1.3797

ElGamal, R., Song, C., Rayan, A. M., Liu, C., Al-Rejaie, S., & ElMasry, G. (2023). Thermal degradation of bioactive compounds during drying process of horticultural and agronomic products: A comprehensive overview. Agronomy, 13(6). https://doi.org/10.3390/agronomy13061580

Gandjar, I. G., & Rohman, A. (2007). Kimia farmasi analisis. Yogyakarta: Pustaka Pelajar.

Glasenapp, Y., Korth, I., Nguyen, X. V, & Papenbrock, J. (2019). Sustainable use of mangroves as sources of valuable medicinal compounds: Species identification, propagation and secondary metabolite composition. South African Journal of Botany, 121, 317–328. https://doi.org/10.1016/j.sajb.2018.11.020

Hamka, Z., & Arief, R. (2022). Pengaruh Metode Maserasi Bertingkat Terhadap Nilai Rendemen Dan Profil Kramotografi Lapis Tipis (Klt) Ekstrak Daun Kemangi (Ocimum Basilicum L. Jurnal Kesehatan Yamasi Makassar, 6(1), 154–162. Retrieved from https://jurnal.yamasi.ac.id/index.php/Jurkes/article/view/213

Hasnaeni, H., & Wisdawati, W. (2019). Pengaruh metode ekstraksi terhadap rendemen dan kadar fenolik ekstrak tanaman Kayu Beta-beta (Lunasia amara Blanco. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)(e-Journal, 5(2), 175–182. https://doi.org/10.22487/j24428744.2019.v5.i2.13599

Jha, N., Madasamy, S., Prasad, P., Lakra, A. K., Tilwani, Y. M., & Arul, V. (2022). Physico-chemical and functional characterization of polysaccharide purified from mangrove Rhizophora mucronata leaves having potent biological activity. South African Journal of Botany, 147, 659–669. https://doi.org/10.1016/j.sajb.2022.02.036

Karthika, K., & Paulsamy, S. (2015). TLC and HPTLC fingerprints of various secondary metabolites in the stem of the traditional medicinal climber, Solena amplexicaulis. Indian Journal of Pharmaceutical Sciences, 77(1), 111. https://doi.org/10.4103/0250-474x.151591

Kumar, M. K., & Pola, S. (2023). Mangrove species as a potential source of bioactive compounds for diverse therapeutic applications. In Marine Antioxidants (pp. 249–263). Academic Press. https://doi.org/10.1016/B978-0-323-95086-2.00020-5

La, E. O. J., Sawiji, R. T., & Yuliawati, A. N. (2020). Skrining fitokimia dan analisis kromatografi lapis tipis ekstrak etanol kulit buah naga merah (Hylocereus polyrhizus. Indonesian Journal of Pharmacy and Natural Product, 3(1). https://doi.org/10.35473/ijpnp.v3i1.503

Martinez-Burgos, W. J., Montes Montes, E., Pozzan, R., Serra, J. L., Torres, D. O., Manzoki, M. C., & Soccol, C. R. (2024). Bioactive Compounds Produced by Macromycetes for Application in the Pharmaceutical Sector: Patents and Products. Fermentation, 10(6), 275. https://doi.org/10.3390/fermentation10060275

Muliyana, M. (2020). Kajian pemanfaatan ekstrak daun bakau sebagai agen antifertilitas. Retrieved from http://etheses.uinmataram.ac.id/id/eprint/1514

Mutha, R. E., Tatiya, A. U., & Surana, S. J. (2021). Flavonoids as natural phenolic compounds and their role in therapeutics: An overview. Future Journal of Pharmaceutical Sciences, 7, 1–13. https://doi.org/10.1186/s43094-020-00161-8

Mutik, M. S., Sibero, M. T., Widianingsih, W., Subagiyo, S., Pribadi, R., Haryanti, D., & Murwani, R. (2022). Kandungan senyawa bioaktif dan aktivitas biologis ekstrak daun Rhizophora apiculata asal Perairan Teluk Awur, Jepara. Jurnal Kelautan Tropis, 25(3), 378–390. https://doi.org/10.14710/jkt.v25i3.14287

Nasim, N., Sandeep, I. S., & Mohanty, S. (2022). Plant-derived natural products for drug discovery: current approaches and prospects. The Nucleus, 65(3), 399–411. https://doi.org/10.1007/s13237-022-00405-3

Nieto, G., Martínez-Zamora, L., Peñalver, R., Marín-Iniesta, F., Taboada-Rodríguez, A., López-Gómez, A., & Martínez-Hernández, G. B. (2023). Applications of plant bioactive compounds as replacers of synthetic additives in the food industry. Foods, 13(1), 47. https://doi.org/10.3390/foods13010047

Pratiwi, S. A., Februyani, N., & Basith, A. (2023). Skrining dan Uji Penggolongan Fitokimia dengan Metode KLT pada Ekstrak Etanol Kemangi (O. Sereh Dapur (ed.)). Retrieved from https://repository.unugiri.ac.id:8443/id/eprint/5289/1/Jurnal+Sinta+5+Shoffi+Ajeng (2).pdf

Rahayu, S., Rozirwan, R., & Purwiyanto, A. I. S. (2019). Daya hambat senyawa bioaktif pada mangrove Rhizophora Sp. sebagai antibakteri dari perairan Tanjung Api-Api, Sumatera Selatan. Jurnal Penelitian Sains, 21(3), 151–162. https://doi.org/10.56064/jps.v21i3.544

Ridlo, A., Pramesti, R., Koesoemadji, K., Supriyantini, E., & Soenardjo, N. (2017). Aktivitas antioksidan ekstrak daun mangrove Rhizopora mucronata. Buletin Oseanografi Marina, 6(2), 110–116. Retrieved from https://shorturl.asia/x5eK8

Ridlo, A., Supriyantini, E., & Sedjati, S. (2019). Kandungan total fenolat pada ekstrak Rhizophora sp dari Teluk Awur, Jepara. Jurnal Kelautan Tropis, 22(1), 27–34. https://doi.org/10.14710/jkt.v22i1.4304

Rosulva, I., Hariyadi, P., Budijanto, S., & Sitanggang, A. B. (2022). Potensi buah mangrove sebagai sumber pangan alternatif. Jurnal Teknologi Hasil Pertanian, 14(2). https://doi.org/10.20961/jthp.v14i2.55509

Roy, M., & Dutta, T. K. (2021). Evaluation of phytochemicals and bioactive properties in mangrove associate Suaeda monoica Forssk. Ex JF Gmel. of Indian Sundarbans. Frontiers in Pharmacology, 12, 584019. https://doi.org/10.3389/fphar.2021.584019

Rozirwan, R., Hananda, H., Nugroho, R. Y., Apri, R., Khotimah, N. N., Fauziyah, F., & Aryawati, R. (2023). Antioxidant Activity, Total Phenolic, Phytochemical Content, and HPLC Profile of Selected Mangrove Species from Tanjung Api-Api Port Area, South Sumatra, Indonesia. Tropical Journal of Natural Product Research, 7(7). Retrieved from https://tjnpr.org/index.php/home/article/view/2250

Rumengan, A. P., Mandiangan, E. S., Tanod, W. A., Paransa, D. S. J., Paruntu, C. P., & Mantiri, D. M. H. (2021). Identification of pigment profiles and antioxidant activity of Rhizophora mucronata mangrove leaves origin Lembeh, North Sulawesi. Biodiversitas Journal of Biological Diversity. Retrieved from https://repo.unsrat.ac.id/4596/7/DOC-20230627-WA0004..pdf

Saifudin, A. (2014). Senyawa alam metabolit sekunder teori, konsep, dan teknik pemurnian. Deepublish.

Sanjaya, Y. A., Pratiwi, Y. S., Hendrawan, E. P. N., Salsabila, Z. N., & Amalia, T. (2023). Potency of Mangrove Leaves (Rhizophora mucronata) Containing Bioactive Compounds as Source of Antioxidant: A Review. International Journal of Eco-Innovation in Science and Engineering, 4(2). https://doi.org/10.33005/ijeise.v4i2.120

Sari, A., Dahlan, D., Prayitno, Y., Tuhumury, R. A., Siegers, W. H., Kurniawan, A., & Ahmad, I. (2023). Persepsi Masyarakat terhadap Pengelolaan Wisata Mangrove Terpadu di Kawasan Taman Wisata Alam Teluk Youtefa. Jurnal Sosial Ekonomi Kelautan Dan Perikanan, 18(2), 211–225. https://doi.org/10.15578/jsekp.v18i2.12103

Sari, R. N. (2021). Pemanfaatan Ekstrak Daun Bakau (Rhizopora Sp) Dalam Pembuatan Roti Manis Yang Ditambahkan Tepung Pisang [Universitas Negeri Makassar]. Retrieved from http://eprints.unm.ac.id/id/eprint/20205

Sibero, M. T., Igarashi, Y., Radjasa, O. K., Sabdono, A., Trianto, A., Zilda, D. S., & Wijaya, Y. J. (2019). Sponge-associated fungi from a mangrove habitat in Indonesia: species composition, antimicrobial activity, enzyme screening and bioactive profiling. International Aquatic Research, 11, 173–186. https://doi.org/10.1007/s40071-019-0227-8

Souhoka, F. A., Hattu, N., & Huliselan, M. (2019). Uji Aktivitas Antioksidan Ekstrak Metanol Biji Kesumba Keling (Bixa orellana L. Indonesian Journal of Chemical Research, 7(1), 25–31. https://doi.org/10.30598/ijcr.2019.7-fas

Sun, W., & Shahrajabian, M. H. (2023). Therapeutic potential of phenolic compounds in medicinal plants—Natural health products for human health. Molecules, 28(4). https://doi.org/10.3390/molecules28041845

Syawal, H., Hakim, L., & Effendi, I. (2020). Phytochemical analysis of Rhizophora apiculata leaf extract and its inhibitory action against Staphylococcus aureus, Aeromonas hydrophila and Pseudomonas aeruginosa. Aquaculture, Aquarium, Conservation & Legislation, 13(4), 2242–2249. Retrieved from http://www.bioflux.com.ro/docs/2020.2242-2249.pdf

Wardani, Y. K., Kristiani, E. B. E., & Sucahyo, S. (2020). Korelasi Antara Aktivitas Antioksidan dengan Kandungan Senyawa Fenolik dan Lokasi Tumbuh Tanaman Celosia argentea Linn. Bioma: Berkala Ilmiah Biologi, 22(2), 136–142. https://doi.org/10.14710/bioma.22.2.136-142

Widarta, I. W. R., & Wiadnyani, A. A. I. S. (2019). Pengaruh metode pengeringan terhadap aktivitas antioksidan daun alpukat. Jurnal Aplikasi Teknologi Pangan, 8(3), 80–85. https://doi.org/10.17728/jatp.3361

Zeb, A., & Murkovic, M. (2010). Thin-layer chromatographic analysis of carotenoids in plant and animal samples. JPC–Journal of Planar Chromatography–Modern TLC, 23, 94–103. https://doi.org/10.1556/JPC.23.2010.2.1

Zulfajri, M. (2019). Antioxidant Activity From SyzygiumCumini (L.) Skeels. Journal of Physics: Conference Series, 1232(1), 12009. https://doi.org/10.1088/1742-6596/1232/1/012009

Author Biographies

Dirk Y. P. Runtuboi, Cenderawasih University

Ervina Indrayani, Cenderawasih University

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