Repellent Bioactivity of Lantana camara Leaf Extract Against Culex Mosquitoes
DOI:
10.29303/jppipa.v11i2.9586Published:
2025-02-28Downloads
Abstract
The increasing resistance of mosquitoes to chemical insecticides, which negatively impacts the environment, necessitates alternative plant extract usage to mitigate these effects. The objective of this study was to evaluate the bioactivity of Lantana camara leaf extract as a repellent against Culex mosquitoes. L. camara leaves were extracted using the maceration method. Concentrations of 1%, 2%, 3%, and 4% L. camara leaf extract were used to test repellent efficacy. The arm-in-cage method was used to assess effectiveness. Key parameters observed included the number of mosquito landings, time to first bite, and duration of protection. Results indicated that a 4% concentration of L. camara leaf extract provided optimal protection, reducing mosquito landings by up to 90% and offering a two-hour protection duration. This efficacy was comparable to commercial repellents, which provided 96% protection. These findings suggest that L. camara leaf extract has the potential to serve as an effective, safe, and environmentally friendly mosquito repellent.
Keywords:
Bioactivity, Lantana camara, Mosquito, RepellentReferences
Abbas, M. G., Azeem, M., Bashir, M. U., Ali, F., Mozūratis, R., & Binyameen, M. (2024). Chemical Composition, Repellent, and Oviposition Deterrent Potential of Wild Plant Essential Oils against Three Mosquito Species. Molecules, 29(11). https://doi.org/10.3390/molecules29112657
Alghamdi, A. A. (2021). Evaluation of leaves and flowers acetone extracts of Lantana camara Linn as larvicidal agents against. Anopheles arabiensis and Culex quinquefasciatus larvae. 6(1), 75–78.
Bakri, R., & Jadkarim, R. J. (2025). Tropical and Vectors-Borne Diseases: Insights into Biology, Transmission, and Control Measures. In D. M. A. Sperança (Ed.), Mosquito-Borne Tropical Diseases. IntechOpen. https://doi.org/10.5772/intechopen.1007959
Bhargava, D. S., Agrawal, D., & Agrawal, O. P. (2013). Repellent Activity of Essential Oil and Leaf extract of Lantana camara L. In Laboratory condition. Retrieved from https://api.semanticscholar.org/CorpusID:212593870.
Bhuvaneswari, E., & Giri, R. S. (2018). Physicochemical and phytochemical screening in Lantana camara leaves. ~ 1962 ~ Journal of Pharmacognosy and Phytochemistry, 7(6), 1962–1966.
Brugman, V. A., Hernández-Triana, L. M., Medlock, J. M., Fooks, A. R., Carpenter, S., & Johnson, N. (2018). The role of Culex pipiens L. (Diptera: Culicidae) in virus transmission in Europe. International Journal of Environmental Research and Public Health, 15(2). https://doi.org/10.3390/ijerph15020389
Dua, V. K., Pandey, A. C., Singh, R., p. Sharma, V., & Subbarao, S. K. (2003). Isolation of repellent ingredients from Lantana camara (Verbenaceae) flowers and their repellency against Aedes mosquitoes. Journal of Applied Entomology, 127. https://api.semanticscholar.org/CorpusID:83544767
Edwin, O. A., Sellah, K., AnthoneySwamy, T., & Mutuku, N. C. (2014). Repellency of Lantana camara leaves smoke against female anopheles mosquitoes. International Journal of Bioassays, 3, 1695–1698. https://api.semanticscholar.org/CorpusID:55278332
Edy, H. J., & Parwanto, M. E. (2020). Aktivitas antimikroba dan potensi penyembuhan luka ekstrak tembelekan (Lantana camara Linn.). Jurnal Biomedika Dan Kesehatan, 3(1), 33–38. https://doi.org/10.18051/jbiomedkes.2020.v3.33-38
Ghosh, S., Sen, R., Datta, A., Banerjee, P. K., & Quadros, S. (2024). Evaluation of larvicidal properties of two Indian plants (Lantana camara and Cinnamomum tamala) solvent extracts against mosquito larvae (Aedes sp. and Culex sp.) and their phytochemical composition through spectroscopy. International Journal of Mosquito Research, 11(4), 52–63. https://doi.org/10.22271/23487941.2024.v11.i4a.789
Hemalatha, P., Elumalai, D., Janaki, A., Velu, K., Velayutham, K., & Kaleena, P. K. (2015). Against Three Important Mosquito Species. 3(1), 174–181.
Hoang, T. C., Nguyen, M. T., Nguyen, T. Q., Ho, B. T. Q., Nguyen, H. T., Ngo, T. P. D., Tran, H. N. K., & Bui, T. K. L. (2024). In vitro anti-leukemia, antioxidant, and anti-inflammatory properties of Lantana camara. Brazilian Journal of Biology = Revista Brasleira de Biologia, 84, e279899. Retrieved from https://api.semanticscholar.org/CorpusID:270193689
Ifora, I., Fauziah, F., & Mayora, S. A. (2020). Aktivitas Anti-inflamasi dan Daya Hambat Siklooksigenase-2 Ekstrak Etanol Daun Tembelekan (Lantana camara L.). Retrieved from https://api.semanticscholar.org/CorpusID:226040992
Madhav, M., Blasdell, K. R., Trewin, B., Paradkar, P. N., & López-Denman, A. J. (2024). Culex-Transmitted Diseases: Mechanisms, Impact, and Future Control Strategies using Wolbachia. Viruses, 16(7), 1–24. https://doi.org/10.3390/v16071134
Mondal, S., Ghosh, S., Maity, S., Ghosal, G., & Sultana, A. (2023). Comparative study on larvicidal potentials of three medicinal plants on larvae of Culex quinquefasciatus Say, 1823 mosquitoes. International Journal of Mosquito Research, 10(4), 54–61. https://doi.org/10.22271/23487941.2023.v10.i4a.687
Ordanza-Cortez, A. (2015). Insecticidal effects of leaves, flowers and fruits of Lantana camara Linn. (Philippine Kantutay) on Musca domestica L. (Philippine Houseflies). Journal of Natural Product and Plant Resources, 5, 26–35. https://api.semanticscholar.org/CorpusID:218109105
Rajan, D. S., & Varghese, T. A. (2017). An evaluation on the larvicidal efficacies of aqueous leaf extracts of Lantana camara and Catharanthus roseus against mosquito larvae. Int J Mosq Res, 4(2), 93–97.
Rajashekar, Y., Ravindra, K. V, & Bakthavatsalam, N. (2014). Leaves of Lantana camara Linn. (Verbenaceae) as a potential insecticide for the management of three species of stored grain insect pests. Journal of Food Science and Technology, 51, 3494–3499. https://api.semanticscholar.org/CorpusID:46216654
Soares de Oliveira, M. A., Melo Coutinho, H. D., Jardelino de Lacerda Neto, L., Castro de Oliveira, L. C., & Bezerra da Cunha, F. A. (2020). Repellent activity of essential oils against culicids: A review. Sustainable Chemistry and Pharmacy, 18(October). https://doi.org/10.1016/j.scp.2020.100328
Venu, S., Sivakumar, J., Dhivya, R., Bhuvaneswari, S., & Rajkumar, M. (2023). Effect of Ethanolic and Chloroform Extracts of Lantana Camara Flowers on the Second Instar Stage of Anopheles Mosquito Larvae. Asian Journal of Science and Applied Technology, 12(1), 54–61. https://doi.org/10.51983/ajsat-2023.12.1.3530
Wahyuningrum, R., E, G., & IN, P. (2021). Aktivitas Antimikroba Dan Antioksidan Ekstrak Dan Fraksi Daun Tembelekan (Lantana camara L.). Jurnal Farmasi Udayana, 10(1), 107. https://doi.org/10.24843/jfu.2021.v10.i01.p13
WHO. (2009). Guidelines for efficacy testing of mosquito repellents for human skin. Who/Htm/Ntd/Whopes/2009.4, 1–6.
Zeeshan, M., & Kukshal, M. (2023). a Review of Therapeutic Properties of Lantana Camara. 8(6), 831. Retrieved from www.ijnrd.org
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