Formulation, Stability, and Activity Test of Sunscreen Cream from Cactus Stem Extract (Opuntia Cochenillifera (L.) Mill) Using an Ultraviolet-Visible Spectrophotometer
DOI:
10.29303/jppipa.v12i5.15183Published:
2026-05-25Downloads
Abstract
Sunlight has several health benefits, but it also has certain negative impacts. Sunscreen is a cosmetic product that protects the skin from ultraviolet rays, which can cause a number of skin health problems. Phenolic compounds, particularly flavonoids, have the potential to be used in sunscreen cosmetics. The goal of this research is to develop a sunscreen cream using the active ingredient Centong cactus stem extract (Opuntia cochenillifera (L.) Mill) and evaluate its stability and Sun Protection Factor (SPF) using a spectrophotometer. The results showed that the formulation of Centong cactus stem extract sunscreen cream met the criteria set regarding its physical and chemical properties based on the Indonesian National Standard (SNI) 2016-4399-1996. These properties include organoleptic characteristics, homogeneity, spreadability, adhesion, pH, viscosity, and stability. The sunscreen activity test resulted in an SPF rating of 7.04 ± 0.32 for the first f ormulation (FI) for extra protection, 12.02 ± 0.34 for the second formulation (FII) for maximum protection, and 18.03 ± 0.31 for the third formulation (FIII) for ultra protection. The results of this initial study indicate that Centong cactus stem extract sunscreen cream has good stability and ultra-sun protection factor FIII (15%) activity, which is very good for further research.
Keywords:
Cream Stem cactus centong (Opuntia cochenillifera (L.) Mill) SPF SunscreenReferences
Agustin, F. D., Indratmoko, S., & Yulianto, A. N. (2024). Formulasi dan Evaluasi Krim Tabir Surya Ekstrak Kulit Jeruk Lemon (Citrus Limon L.) dan Nanosqualene Sebagai Anti-Aging. Sains Indonesiana, 2(4), 10–27. Retrieved from https://sainsindonesiana.id/index.php/sainsindonesiana/article/view/75
Amini, A., Hamdin, C. D., Muliasari, H., & Subaidah, W. A. (2020). Efektivitas formula krim tabir surya berbahan aktif ekstrak etanol biji wali (Brucea javanica L. Merr). Jurnal Kefarmasian Indonesia, 50–58. https://doi.org/10.22435/jki.v10i1.2066 DOI: https://doi.org/10.22435/jki.v10i1.2066
Amrane-Abider, M., Imre, M., Herman, V., Debbou-Iouknane, N., Zemouri-Alioui, S., Khaled, S., Bouiche, C., Ner’in, C., Acaroz, U., & Ayad, A. (2023). Bioactive compounds and in vitro antioxidant and anticoccidial activities of Opuntia ficus-indica flower extracts. Biomedicines, 11(8), 2173. https://doi.org/10.3390/biomedicines11082173 DOI: https://doi.org/10.3390/biomedicines11082173
Anggreini, D., Saputri, M., & Sari, N. (2024). Mengenal lebih dekat nilai SPF (Sun protecting factor) dalam kosmetik. Jurnal Pengabdian Masyarakat Tjut Nyak Dhien, 3(1), 33–38. Retrieved from https://journal.utnd.ac.id/index.php/JPMTND/article/view/1008 DOI: https://doi.org/10.36490/jpmtnd.v3i1.1008
Astryna, S. Y., Alvionida, F., Elizar, E., Meilina, R., & Husna, A. (2025). Uji Aktivitas Tabir Surya Ekstrak Etil Asetat Daun Pepaya (Carica papaya L.). JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE, 11(1), 694–700. https://doi.org/10.33143/jhtm.v11i1.5252
Cahyati, A., Arifin, S., & Abror, M. (2022). The Potential of Centong Cactus (Opuntia cochenillifera) as a Remediation Agent for Sidoarjo Mud Polluted Soil with Indicators of Fe Content Reduction and Plant Growth: Potensi Kaktus Centong (Opuntia cochenillifera) Sebagai Agen Remediasi Tanah Tercemar . Procedia of Engineering and Life Science, 2(2). https://doi.org/10.21070/pels.v2i2.1269 DOI: https://doi.org/10.21070/pels.v2i2.1269
Dewi, K. R. S., & Yowani, S. (2023). Eksplorasi potensi bahan alam sebagai tabir surya. COMSERVA: Jurnal Penelitian Dan Pengabdian Masyarakat, 3(08), 2924–2935. Retrieved from https://shorturl.asia/EeRyq DOI: https://doi.org/10.59141/comserva.v3i08.1105
Dwiastuti, R., & ARDIYATI, S. H. E. (2021). Formulasi Sediaan Gel Nanopartikel Lipid Ekstrak Daun Bi-Nahong (Anredera cordifolia (Ten.) Steenis). Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ): Universitas Sam Ratulangi, 3(2), 40. Retrieved from https://elibrary.ru/item.asp?id=75311177 DOI: https://doi.org/10.35799/pmj.3.2.2020.32879
Erwiyani, A. R., Cahyani, A. S., Mursyidah, L., Sunnah, I., & Pujistuti, A. (2021). Formulasi dan Evaluasi Krim Tabir Surya Ekstrak Daging Labu Kuning (Cucurbita maxima). Majalah Farmasetika, 6(5), 386–397. https://doi.org/10.24198/mfarmasetika.v6i5.35969 DOI: https://doi.org/10.24198/mfarmasetika.v6i5.35969
Fardanu, A. R., Suprapto, S., & others. (2026). Optimasi Formula Patch Anti Jerawat Dari Ekstrak Batang Pisang Ambon dengan HPMC-Kitosan menggunakan Simplex Lattice Design. Journal of Pharmaceutical and Sciences, 184–194. https://doi.org/10.36490/journal-jps.com.v9i1.1289 DOI: https://doi.org/10.36490/journal-jps.com.v9i1.1289
Handoyo, D. L. Y., & Pranoto, M. E. (2020). the effect of drying temperature variations on making neem leaf simplicia (Azadirachta indica). Tinctura Pharmaceutical Journal, 1(2), 45–54. Retrieved from https://shorturl.asia/obqWs DOI: https://doi.org/10.35316/tinctura.v1i2.988
Hidayah, H., Mentari, M., Warsito, A. M. P., Dinanti, D., & others. (2023). Potensi Aktivitas Antioksidan Dari Berbagai Tanaman Untuk Tabir Surya. Journal of Pharmaceutical and Sciences, 409–415. https://doi.org/10.36490/journal-jps.com.v6i2.119 DOI: https://doi.org/10.36490/journal-jps.com.v6i2.119
Inaku, C., Aliah, A. I., & Marlina, M. (2023). Potensi Tabir Surya Formula Sediaan Krim Ekstrak Etanol Buah Pare (Momordica charantia L). Jurnal Ilmiah Farmako Bahari, 14(2), 210–224. https://doi.org/10.52434/jifb.v14i2.2643 DOI: https://doi.org/10.52434/jifb.v14i2.2643
Irianto, M., Brahmana, N. B., & Munthe, A. R. (2022). Kegiatan Pemanfaatan Kaktus Centong Sebagai Antibakteri Pada Pertumbuhan Bakteri Staphylacoccus epidermis. Jurnal Abdimas Mutiara, 3(2), 433–435. Retrieved from https://e-journal.sari-mutiara.ac.id/index.php/JAM/article/view/4034
Lumantow, V. S., Edy, H. J., & Siampa, J. P. (2023). Formulasi Dan Penentuan Nilai Spf Krim Tabir Surya Ekstrak Kulit Buah Lemon Suanggi (Citrus Limon (L.) Burm. F.) Secara In Vitro. Pharmacon, 12(3), 338–348. Retrieved from https://shorturl.asia/JIueD DOI: https://doi.org/10.35799/pha.12.2023.49023
Marayart, S., Konmun, H., Jampasri, K., & Saeng-ngam, S. (2025). Total phenolic, flavonoid contents, and antioxidant activity of strawberries and local medicinal plants. Asia-Pacific Journal of Science and Technology, 30(2), APST--30. Retrieved from https://so01.tci-thaijo.org/index.php/APST/article/download/266543/179421
Novitasari, A. (2016). Isolasi dan identifikasi saponin pada ekstrak daun mahkota dewa dengan ekstraksi maserasi. Jurnal Sains, 6(12). Retrieved from http://journal.unigres.ac.id/index.php/Sains/article/view/577
Novitasari, H., Nashihah, S., & Zamzani, I. (2021). Identifikasi Daun Sangkareho (Callicarpa longifolia Lam) secara Makroskopis dan Mikroskopis: Macroscopic and Microscopic Identification of Sangkareho (Callicarpa longifolia Lam.) Leaves. Jurnal Sains Dan Kesehatan, 3(5), 667–672. Retrieved from https://jsk.ff.unmul.ac.id/index.php/JSK/article/view/485 DOI: https://doi.org/10.25026/jsk.v3i5.570
NurKhotimah, F., Ahwan, A., & Qonitah, F. (2024). Uji Sun Protecting Factor (SPF) Formulasi Ekstrak Air, Etanol Dan Kloroform Daun Teh Hijau (Camellia sinensis L.) Sebagai Krim Tabir Surya [Unversitas Sahid Surakarta]. Retrieved from https://repository.usahidsolo.ac.id/3092/
Parawansya, O. I., Legasari, L., Iskandar, D., & Yani, D. F. (2024). Determination Of Sun Protection Factor (SPF) Value Of Endophyte Fungi From Sendok Leaves (Plantago Major L.). ALKIMIA: Jurnal Ilmu Kimia Dan Terapan, 8(2). https://doi.org/10.19109/h5w9wy05
Pratikto, A. P., Yamlean, P. V. Y., & Siampa, J. P. (2024). Formulasi dan evaluasi krim ekstrak kulit jeruk nipis (Citrus aurantifolia) sebagai tabir surya. Pharmacon, 13(1), 483–495. Retrieved from https://shorturl.asia/0J5jm
Pujiastuti, E., & Islamiyati, R. (2021). Antioxidant activity of ethyl acetate fraction and water of parijoto fruit twigs (Medinilla speciosa Blume) by scavenging DPPH free radicals. Cendekia Journal of Pharmacy, 135–144. Retrieved from https://shorturl.asia/JORVM DOI: https://doi.org/10.31596/cjp.v5i2.143
Puspitasari, A. D., Mulangsri, D. A. K., & Herlina, H. (2018). Formulasi krim tabir surya ekstrak etanol daun kersen (Muntingia calabura l.) untuk kesehatan kulit. Media Penelitian Dan Pengembangan Kesehatan, 28(4), 263–270. https://doi.org/10.22435/mpk.v28i4.524 DOI: https://doi.org/10.22435/mpk.v28i4.524
Rahman, I. I., Delima, D., NurFauziyya, L. A., Lingga, L., & Rasydy, L. O. A. (2025). Spektrofotometri UV-VIS dalam Penentuan Nilai SPF pada Tabir Surya Ekstrak Alam. Jurnal Kesehatan Amanah, 9(1), 386–395. https://doi.org/10.57214/jka.v9i1.901 DOI: https://doi.org/10.57214/jka.v9i1.901
Rahmawati, I., Jumpeno, E. B., Mellawati, J., & Ramlan, R. (2023). Analisis Pengaruh Densitas Terhadap Potensi Komposit Apron Proteksi Radiasi Sinar-X dengan Bahan Kaktus Centong dan Timbal (II) Asetat. Jurnal Penelitian Sains, 25(2), 125–130. https://doi.org/10.56064/jps.v25i2.784 DOI: https://doi.org/10.56064/jps.v25i2.784
Ramdan, S. R. K., Purwanti, D., Kurniasih, N., & Harun, N. (2023). Formulasi Dan Nilai Spf Krim Tabir Surya Kombinasi Ekstrak Pegagan (Centella Asiatica L) Dengan Tio2: Formulation And Spf Value Sunscreen Cream Combination Gotu Kola Extract (Centella asiatica L) With TiO2. Medical Sains: Jurnal Ilmiah Kefarmasian, 8(2), 373–382. Retrieved from https://ojs.ummada.ac.id/index.php/iojs/article/view/302/428 DOI: https://doi.org/10.37874/ms.v8i2.302
Rizal, R., Salman, S., & Maharani, V. (2023). Formulasi sediaan spray gel ekstrak etanol pegagan (Centella asiatica (L.) Urban) dan uji daya tabir surya. Jurnal Sains Farmasi Dan Kesehatan, 1(1), 48–59. Retrieved from https://shorturl.asia/lkYA0 DOI: https://doi.org/10.62379/jfkes.v1i1.83
Sari, T. M., Agustin, D., Fatma, Y., & others. (2024). Formulasi Sediaan Krim Tabir Surya Fraksi N-Butanol Kulit Batang Rambutan (Nephelium lappaceum L.). Jurnal Kesehatan Perintis, 11(1), 67–73. https://doi.org/10.33653/jkp.v11i1.1063 DOI: https://doi.org/10.33653/jkp.v11i1.1063
Saryanti, D., Setiawan, I., & Safitri, R. A. (2019). Optimization of M/A Cream Formulas From Kepok Banana Peel Extract (Musa acuminata L.). Jurnal Riset Kefarmasian Indonesia, 1(3), 225–237. Retrieved from https://shorturl.asia/2YpnU DOI: https://doi.org/10.33759/jrki.v1i3.44
Simanjuntak, E., Satria, D., & Hasibuan, P. (2026). Cytotoxic Effects of Extract and Fractions of African Leaves (Vernonia amygdalina Delile.) Against WiDr Cells. JURNAL FARMASIMED (JFM), 8(2), 858–865. https://doi.org/10.35451/tf07jx42 DOI: https://doi.org/10.35451/tf07jx42
Singh, M., & Sharma, V. (2016). Spectrophotometric determination of Sun Protection Factor and antioxidant potential of an herbal mixture. British Biotechnology Journal, 10(3), 1–8. Retrieved from https://shorturl.asia/f1yJN DOI: https://doi.org/10.9734/BBJ/2016/21434
Sulistyarini, I., Sari, D. A., & Wicaksono, T. A. (2020). Skrining fitokimia senyawa metabolit sekunder batang buah naga (Hylocereus polyrhizus). Cendekia Eksakta, 5(1). https://doi.org/10.3194/ce.v5i1.3322
Suradnyana, I. G. M., Juliadi, D., & Suena, N. M. D. S. (2023). Formulasi serta uji aktivitas antioksidan dan tabir surya krim ekstrak aseton biji buah alpukat. Jurnal Ilmiah Medicamento, 9(1), 42–51. Retrieved from https://e-journal.unmas.ac.id/index.php/Medicamento/article/download/5504/4611 DOI: https://doi.org/10.36733/medicamento.v9i1.5504
Suryadi, A. M. A., Pakaya, M. S. Y., Djuwarno, E. N., & Akuba, J. (2021). Determination of sun protection factor (SPF) value in lime (citrus aurantifolia) peel extract using UV-Vis spectrophotometry method. Jambura Journal of Health Sciences and Research, 3(2), 169–180. Retrieved from https://doi.org/10.35971/jjhsr.v3i2.10319 DOI: https://doi.org/10.35971/jjhsr.v3i2.10319
Tampubolon, M. I., Priltius, N., & Munthe, A. R. (2022). Uji aktivitas antibakteri ekstrak etanol kaktus centong (Opuntia cochenillifera) terhadap pertumbuhan bakteri Staphylacoccus epidermidis dengan media buatan pati pisang kepok (Musa paradisiaca). JURNAL TEKNOLOGI KESEHATAN DAN ILMU SOSIAL (TEKESNOS), 4(1), 398–406. Retrieved from https://e-journal.sari-mutiara.ac.id/index.php/tekesnos/article/view/4160
Tari, M., & Indriani, O. (2023). Formulasi dan uji stabilitas fisik sediaan krim ekstrak sembung rambat (Mikania micrantha kunth). Babul Ilmi Jurnal Ilmiah Multi Science Kesehatan, 15(1). https://doi.org/10.36729/bi.v15i1.1074 DOI: https://doi.org/10.36729/bi.v15i1.1074
Tungadi, R., Pakaya, M. S., & others. (2023). Formulasi dan evaluasi stabilitas fisik sediaan krim senyawa astaxanthin. Indonesian Journal of Pharmaceutical Education, 3(1). https://doi.org/10.37311/ijpe.v3i1.14612 DOI: https://doi.org/10.37311/ijpe.v3i1.14612
Utami, Y. P., Umar, A. H., Syahruni, R., & Kadullah, I. (2017). Standardisasi simplisia dan ekstrak etanol daun leilem (Clerodendrum minahassae Teisjm. & Binn.). Journal of Pharmaceutical and Medicinal Sciences, 2(1). Retrieved from https://shorturl.asia/5vqjF DOI: https://doi.org/10.35799/pmj.1.2.2018.21655
Widiasriani, I. A. P., Udayani, N. N. W., Triansyah, G. A. P., Dewi, N. P. E. M. K., Wulandari, N. L. W. E., & Prabandari, A. A. S. S. (2024). Artikel Review: Peran Antioksidan Flavonoid dalam Menghambat Radikal Bebas. Journal Syifa Sciences and Clinical Research, 6(2). https://doi.org/10.37311/jsscr.v6i2.27055 DOI: https://doi.org/10.37311/jsscr.v6i2.27055
Widodo, S., Susanti, L., Samsuar, A. H., & Safitri, A. (2024). Formulasi Krim Anti Acne Ekstrak Etanol Kulit Kentang (Solanum tuberosum L.) Dan Aktivitas Antibakteri Terhadap Staphylococcus epidermidis Dan Propionibacterium acnes. Anti Acne Cream Formulation Of Potato Ethanol Extracts (Solanum tuberosum L.) And Antib. Jurnal Farmasi Lampung Vol, 13(1). Retrieved from https://shorturl.asia/g7jm5 DOI: https://doi.org/10.37090/jfl.v13i1.1646
Yana, N. D., Gummay, B., & Marpaung, M. P. (2022). Analisis Parameter Spesifik dan Nonspesifik Simplisia Daun Bawang Merah (Allium cepa L.). KOVALEN: Jurnal Riset Kimia, 8(1), 45–52. https://doi.org/10.22487/kovalen.2022.v8.i1.15741 DOI: https://doi.org/10.22487/kovalen.2022.v8.i1.15741
Yang, S. I., Liu, S., Brooks, G. J., Lanctot, Y., & Gruber, J. V. (2018). Reliable and simple spectrophotometric determination of sun protection factor: A case study using organic UV filter-based sunscreen products. Journal of Cosmetic Dermatology, 17(3), 518–522. https://doi.org/10.1111/jocd.12390 DOI: https://doi.org/10.1111/jocd.12390
Zulkarnain, A. K., Syach, M. F., & Ritmaleni, R. (2024). Formulasi dan Uji Stabilitas Fisik Sediaan Krim Tabir Surya Pentagamavunon-5 Serta Uji Aktivitasnya Secara In Vitro. MAJALAH FARMASEUTIK: Universitas Gadjah Mada, 20(2), 145. Retrieved from https://www.elibrary.ru/ip_blocked.asp DOI: https://doi.org/10.22146/farmaseutik.v20i2.95459
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