Toothpaste Formulation Ethanol Extract Mangosteen Peel (Garcinia mangostana L.) and Test Activity Against Candida albicans

Authors

Nur Khairun Nisa Junuda , Ermina Pakki , Nur Ida

DOI:

10.29303/jppipa.v9i6.3623

Published:

2023-06-25

Issue:

Vol. 9 No. 6 (2023): June

Keywords:

Antifungals, Candidiasis, Candida albicans, Mangosteen peel, Toothpastes

Research Articles

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How to Cite

Junuda, N. K. N. ., Pakki, E., & Ida, N. . (2023). Toothpaste Formulation Ethanol Extract Mangosteen Peel (Garcinia mangostana L.) and Test Activity Against Candida albicans. Jurnal Penelitian Pendidikan IPA, 9(6), 4705–4710. https://doi.org/10.29303/jppipa.v9i6.3623
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Abstract

The mangosteen peel contains phenol compounds that have antifungal activity. The study aimed to find out the antifungal activity in the dosage form of toothpaste against Candida albicans. The research methods used include the extraction of mangosteen peel (Garcinia mangostana L.) by maceration using 96% ethanol. The toothpaste formula was composed with an extract concentration of 1.25% (F1); 2.5% (F2); 5% (F3); and base (B). Antifungal testing was carried out by diffusion method using Potato Dextrose Agar (PDA) media. The results showed that the toothpaste formula with a concentration of F1; F2; F3; and base (B) has an average value of successive inhibition zone diameters of 11.86 mm; 12.03mm; 12.54mm; and 7.78 mm. The conclusion of the study showed that the toothpaste preparation of the ethanol extract of mangosteen fruit peel (Garcinia mangostana L.) concentration was 1.25%; 2.5%; 5% which performs antifungal activity.

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Author Biographies

Nur Khairun Nisa Junuda, STIKes Karsa Husada Garut, Jawa Barat, Indonesia

Ermina Pakki, Islamic University of Makassar

Nur Ida, Islamic University of Makassar

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Copyright (c) 2023 Nur Khairun Nisa Junuda; Ermin Pakki; Nur Ida

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