Comparison of The Effectiveness Antibacterial Test of Natural Ingredients and Antibiotic in Salmonella typhi Isolated from Hospital Waste and Household Waste

Authors

Syamsul Bahri , Rizal Umami , Ferniawan , Moammar Qadafi , Sekar Partiwi

DOI:

10.29303/jppipa.v9i4.3783

Published:

2023-04-30

Issue:

Vol. 9 No. 4 (2023): April

Keywords:

Antibiotics, Ginger, Salmonella typhi, Turmeric

Research Articles

Downloads

How to Cite

Bahri, S. ., Umami, R. ., Ferniawan, F., Qadafi, M. ., & Partiwi, S. . (2023). Comparison of The Effectiveness Antibacterial Test of Natural Ingredients and Antibiotic in Salmonella typhi Isolated from Hospital Waste and Household Waste. Jurnal Penelitian Pendidikan IPA, 9(4), 2068–2074. https://doi.org/10.29303/jppipa.v9i4.3783

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Abstract

Salmonella typhi is a bacterium that causes salmonellosis which is a serious disease in Indonesia and is still endemic. Until now, the treatment and handling of cases of bacterial infection are still using antibiotics. The comparison of antibacterial effectiveness using turmeric extract, a ginger extract which is a natural ingredient with the antibiotics Ampicillin and Ciprofloxacin on Salmonella typhi isolates from hospital waste and household waste has been conducted. The purpose of this research is to compare the antibacterial effectiveness of Curcuma longa (turmeric) extract, Zingiber officinale (Ginger) extract, Ampicillin, and Ciprofloxacin antibiotics in inhibiting the growth of Salmonella typhi which are isolated from hospital waste and those isolated from household waste. This research is experimental research (experimental), using a control group and the research is carried out in a laboratory. The data collection technique was carried out by measuring the inhibition zone. Size of the inhibition zone of hospital isolates after treated by turmeric and ginger extract is smaller than household isolates. This result indicates that excessive usage of antibiotics will be able to increase the resistance or immunity of Salmonella typhi. Substances which are contained in turmeric and ginger extracts have ability to inhibit the growth of Salmonella typhi, with strong category against hospital isolates and very strong category against household isolates. It is concluded that turmeric and ginger extracts are able to    substitute synthetic antibiotics such as Ampicillin.

References

Afidatul, M., Putri, E., & Latifah, N. (2019). Aktifitas Gel Ekstrak Rimpang Kunyit (Curcuma domestida val) Terhadap Bakteri Staphylococus. Jurnal sains. Health, 3(1). http://dx.doi.org/10.51804/jsh.v3i1.313.45-54

Darmawati, S. & Dewi, SS. (2008). Efek buah Pare (Momordica carantia) Terhadap zona Hambatan Pertumbuhan Salmonella typhi Penyebab Salmonellosis. Jurnal Ilmu Kesehatan, 1(1), 1-6. Retrieved from https://jurnal.unimus.ac.id/index.php/Analis/article/view/195

Depkes RI. (2013). Sistematika Pedoman Penyakit Demam Tifoid. Jakarta: Direktorat Jendral Pengendalian Penyakit dan Penyehatan.

Handayani, M., Suryanto, D., Siregar, T., & Efendi, Z. (2015). Aktivitas Antimikroba Ekstrak Kulit Buah Manggis (Garcinia mangostana) Terhadap Bakteri Aeromonas hydrophila, Edwardsiella tarda Dan Jamur Saprolegnia sp. Aquacoastmarine, 8(3), 11. Retrieved from https://jurnal.usu.ac.id/index.php/aquacoastmarine/article/view/9991

Monica, W. S., Mahatmi, H., & Besung, K. (2013). Pola resistensi Salmonella typhi yang diisolasi dari ikan serigala (Hoplias malabaricus) terhadap antibiotik. Jurnal ilmu dan kesehatan hewan, 1(2), 64-69. Retrieved from https://ojs.unud.ac.id/index.php/jikh/article/view/7143

Nainggolan, R. (2011). Karakteristik Penderita Demam Tifoid. Medan: Fakultas Kesehatan Masyarakat Universitas Sumatera Utara.

Read, A. F., & Woods, R. J. (2014). Antibiotic resistance management. Evolution, medicine, and public health, 2014(1), 147. Retrieved from https://pdfs.semanticscholar.org/a700/906701d768e3378a8a306d103066d050b6bd.pdf

Sulistyarsi, A., & Cahyani, F. M. (2019). Potensi Ekstrak Daun Kamboja Putih dari Madiun dan Magetan sebagai Penghambat Pertumbuhan Bakteri Salmonella typhosa (In Vitro). In Prosiding Seminar Nasional Hasil Penelitian LPPM Universitas PGRI Madiun, 219-227. Retrieved from http://prosiding.unipma.ac.id/index.php/SNHP/article/view/792

Sugiyono. (2011). Metode Penelitian kuantitatif dan kualitatif R&D. Bandung: Alfabeta.

Utami, ER. (2011). Antibiotika, Resistensi, dan Rasionalitas Terapi. El-Hayah, 1(4), 124-138. https://doi.org/10.18860/elha.v1i4.1783

Ventola CL. (2015). The Antibiotic Resistance Crisis: Part 1: Causes and Threats. Pharmacy Therapeutics 40(4), 277-283. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378521/

Walewangko, G. V. C., Bodhi, W., & Kepel, B. J. (2015). Uji resistensi bakteri Escherichia coli yang di isolasi dari plak gigi menggunakan merkuri dan ampisilin. eBiomedik, 3(1). Retrieved from https://ejournal.unsrat.ac.id/v3/index.php/ebiomedik/article/view/6634

Yuliana, A. (2015). Uji Sensitivitas Anti Biotik Levofloxacin Yang Ada Di Pasaran Terhadap Bakteri Salmonella Thyphosa ATTC 2401. Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi, 14(1), 12-17. Retrieved from https://ejurnal.universitas-bth.ac.id/index.php/P3M_JKBTH/article/view/105

Author Biographies

Syamsul Bahri, Sciences Education, Mataram University, Indonesia

Rizal Umami, Department of Biological Sciences Education, Faculty of Teacher Training and Education, Mataram University, Indonesia

Ferniawan, Department of Biological Sciences Education, Faculty of Teacher Training and Education, Mataram University, Indonesia

License

Copyright (c) 2023 Syamsul Bahri, Rizal Umami, Ferniawan, Moammar Qadafi, Sekar Partiwi

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with Jurnal Penelitian Pendidikan IPA, agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, web sites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Jurnal Penelitian Pendidikan IPA.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).