Comparison of The Effectiveness Antibacterial Test of Natural Ingredients and Antibiotic in Salmonella typhi Isolated from Hospital Waste and Household Waste
DOI:
10.29303/jppipa.v9i4.3783Published:
2023-04-30Downloads
Abstract
Salmonella typhi is a bacterium that causes salmonellosis which is a serious disease in Indonesia and is still endemic. Until now, the treatment and handling of cases of bacterial infection are still using antibiotics. The comparison of antibacterial effectiveness using turmeric extract, a ginger extract which is a natural ingredient with the antibiotics Ampicillin and Ciprofloxacin on Salmonella typhi isolates from hospital waste and household waste has been conducted. The purpose of this research is to compare the antibacterial effectiveness of Curcuma longa (turmeric) extract, Zingiber officinale (Ginger) extract, Ampicillin, and Ciprofloxacin antibiotics in inhibiting the growth of Salmonella typhi which are isolated from hospital waste and those isolated from household waste. This research is experimental research (experimental), using a control group and the research is carried out in a laboratory. The data collection technique was carried out by measuring the inhibition zone. Size of the inhibition zone of hospital isolates after treated by turmeric and ginger extract is smaller than household isolates. This result indicates that excessive usage of antibiotics will be able to increase the resistance or immunity of Salmonella typhi. Substances which are contained in turmeric and ginger extracts have ability to inhibit the growth of Salmonella typhi, with strong category against hospital isolates and very strong category against household isolates. It is concluded that turmeric and ginger extracts are able to   substitute synthetic antibiotics such as Ampicillin.
Keywords:
Antibiotics Ginger Salmonella typhi TurmericReferences
Afidatul, M., Putri, E., & Latifah, N. (2019). Aktifitas Gel Ekstrak Rimpang Kunyit (Curcuma domestida val) Terhadap Bakteri Staphylococus. Jurnal sains. Health, 3(1). http://dx.doi.org/10.51804/jsh.v3i1.313.45-54
Darmawati, S. & Dewi, SS. (2008). Efek buah Pare (Momordica carantia) Terhadap zona Hambatan Pertumbuhan Salmonella typhi Penyebab Salmonellosis. Jurnal Ilmu Kesehatan, 1(1), 1-6. Retrieved from https://jurnal.unimus.ac.id/index.php/Analis/article/view/195
Depkes RI. (2013). Sistematika Pedoman Penyakit Demam Tifoid. Jakarta: Direktorat Jendral Pengendalian Penyakit dan Penyehatan.
Handayani, M., Suryanto, D., Siregar, T., & Efendi, Z. (2015). Aktivitas Antimikroba Ekstrak Kulit Buah Manggis (Garcinia mangostana) Terhadap Bakteri Aeromonas hydrophila, Edwardsiella tarda Dan Jamur Saprolegnia sp. Aquacoastmarine, 8(3), 11. Retrieved from https://jurnal.usu.ac.id/index.php/aquacoastmarine/article/view/9991
Monica, W. S., Mahatmi, H., & Besung, K. (2013). Pola resistensi Salmonella typhi yang diisolasi dari ikan serigala (Hoplias malabaricus) terhadap antibiotik. Jurnal ilmu dan kesehatan hewan, 1(2), 64-69. Retrieved from https://ojs.unud.ac.id/index.php/jikh/article/view/7143
Nainggolan, R. (2011). Karakteristik Penderita Demam Tifoid. Medan: Fakultas Kesehatan Masyarakat Universitas Sumatera Utara.
Read, A. F., & Woods, R. J. (2014). Antibiotic resistance management. Evolution, medicine, and public health, 2014(1), 147. Retrieved from https://pdfs.semanticscholar.org/a700/906701d768e3378a8a306d103066d050b6bd.pdf
Sulistyarsi, A., & Cahyani, F. M. (2019). Potensi Ekstrak Daun Kamboja Putih dari Madiun dan Magetan sebagai Penghambat Pertumbuhan Bakteri Salmonella typhosa (In Vitro). In Prosiding Seminar Nasional Hasil Penelitian LPPM Universitas PGRI Madiun, 219-227. Retrieved from http://prosiding.unipma.ac.id/index.php/SNHP/article/view/792
Sugiyono. (2011). Metode Penelitian kuantitatif dan kualitatif R&D. Bandung: Alfabeta.
Utami, ER. (2011). Antibiotika, Resistensi, dan Rasionalitas Terapi. El-Hayah, 1(4), 124-138. https://doi.org/10.18860/elha.v1i4.1783
Ventola CL. (2015). The Antibiotic Resistance Crisis: Part 1: Causes and Threats. Pharmacy Therapeutics 40(4), 277-283. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378521/
Walewangko, G. V. C., Bodhi, W., & Kepel, B. J. (2015). Uji resistensi bakteri Escherichia coli yang di isolasi dari plak gigi menggunakan merkuri dan ampisilin. eBiomedik, 3(1). Retrieved from https://ejournal.unsrat.ac.id/v3/index.php/ebiomedik/article/view/6634
Yuliana, A. (2015). Uji Sensitivitas Anti Biotik Levofloxacin Yang Ada Di Pasaran Terhadap Bakteri Salmonella Thyphosa ATTC 2401. Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi, 14(1), 12-17. Retrieved from https://ejurnal.universitas-bth.ac.id/index.php/P3M_JKBTH/article/view/105
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