Striped Catfish Oil and Turmeric Extract-Reduce Inflammation and Insulin Resistance on Metabolic Syndrom: A Review
DOI:
10.29303/jppipa.v10iSpecialIssue.7440Published:
2024-08-25Issue:
Vol. 10 No. SpecialIssue (2024): Science Education, Ecotourism, Health ScienceKeywords:
Inflammation, Insulin resistance, Metabolic syndrome, Striped catfish oil, Turmeric extractReview
Downloads
How to Cite
Downloads
Metrics
Abstract
Metabolic Syndrome is continuing to grow worldwide. Indonesia is no exception. High-calorie diets and physical inactivity trigger several pathways involved in metabolic syndrome. These include inflammation and insulin resistance. Associated with type 2 diabetes mellitus, cardiovascular disease, and death, metabolic syndrome is important. There is therefore a need for early intervention to reduce the complications of this disease. Striped catfish (Pangasius hypophthalmus) is one of the freshwater fish farmed in Indonesia. Turmeric (Curcuma longa Linn.) is also widely used in Indonesian food preparations. This review aims to focus on striped catfish oil and turmeric extract that positively affect inflammation and insulin resistance in the intervention of metabolic syndrome. This review shows that striped catfish oil contains omega-3 fatty acids (EPA and DHA), while turmeric extract contains flavonoids, tannins, and saponins. Based on the results of the review, it is known that bioactive compounds found in catfish oil and turmeric extract can be used as nutraceutical ingredients to intervene in metabolic syndrome.
References
Agustina, W., Nurhamidah, N., & Handayani, D. (2017). Skrining Fitokimia dan Aktivitas Antioksidan Beberapa Fraksi dari Kulit Batang Jarak (Ricinus communis L.). Jurnal Pendidikan dan Ilmu Kimia, 1(2), 117–122. https://doi.org/10.33369/atp.v1i2.
Akash, M. S. H., Rehman, K., & Liaqat, A. (2017). Tumor Necrosis Factor-Alpha: Role in Development of Insulin Resistance and Pathogenesis of Type 2 Diabetes Mellitus. Journal of Cellular Biochemistry, 1–16. https://doi.org/10.1002/jcb.26174
Alhujaily, M., Dhifi, W., & Mnif, W. (2022). An Overview of the Potential of Medicinal Plants Used in the Development of Nutraceuticals for the Management of Diabetes Mellitus: Proposed Biological Mechanisms. Processes, 10(2044), 1–20. https://doi.org/10.3390/pr10102044
Amalraj, A., Pius, A., Gopi, S., & Gopi, S. (2017). Biological Activities of Curcuminoids, Other Biomolecules from Turmeric and Their Derivatives e A Review. Journal of Traditional and Complementary Medicine, 7, 205–233. https://doi.org/10.1016/j.jtcme.2016.05.005
Ayu, D. F., Diharmi, A., & Ali, A. (2019). Characterization of the Oil from the Abdomen Part of Smoked Catfish (Pangasius hypophthalmus) Processing by-Product (Pangasius hypophthalmus). Jurnal Pengolahan Hasil Perikanan Indonesia, 22(1), 187–197. https://doi.org/10.17844/jphpi.v22i1.26473
Backes, J., Anzalone, D., Hilleman, D., & Catini, J. (2016). The Clinical Relevance of Omega-3 Fatty Acids in the Management of Hypertriglyceridemia. Lipids in Health and Disease, 15(118), 1–12. https://doi.org/10.1186/s12944-016-0286-4
Bernardini, S., Tiezzi, A., Masci, V. L., & Ovidi, E. (2018). Natural Products for Human Health: A Historical Overview of the Drug Discovery Approaches. Natural Product Research, 32(16), 1926–1950. https://doi.org/10.1080/14786419.2017.1356838
Bharti, S. K., Krishnan, S., Kumar, A., & Kumar, A. (2018). Antidiabetic Phytoconstituents and Their Mode of Action on Metabolic Pathways. Therapeutic Advances in Endocrinology and Metabolism Review, 9(3), 81–100. https://doi.org/10.1177/2042018818755019
Bovolini, A., Garcia, J., Andrade, M. A., & Duarte, J. A. (2020). Metabolic Syndrome Pathophysiology and Predisposing Factors. Int J Sports Med. https://doi.org/10.1055/a-1263-0898
Chocair, P. R., Neves, P. D. M. D. M., Sato, V. A. H., Mohrbacher, S., Oliveira, É. S., Pereira, L. V. B., Bales, A. M., Silva, F. P. D., Duley, J. A., & Cuvello-Neto, A. L. (2022). Proposal for Standardizing Normal Insulin Ranges in Brazilian Patients and a New Classification of Metabolic Syndrome. Frontiers in Medicine, 9(984001), 1–9. https://doi.org/10.3389/fmed.2022.984001
Crauste, C., M, R., Thierry, D., & Joseph, V. (2015). Omega-3 Polyunsaturated Lipophenols, How and Why? Biochimie, 120, 62-74. https://doi.org/10.1016/j.biochi.2015.07.018
Dewi, P. J. N., Hartiati, A., & Mulyani, S. (2016). Pengaruh Umur Panen dan Tingkat Maserasi Terhadap Kandungan Kurkumin dan Aktivitas Antioksidan Ekstrak Kunyit (Curcuma domestica Val.). Jurnal Rekayasa dan Manajemen Agroindustri, 4(3), 105–115. Retrieved from https://garuda.kemdikbud.go.id/documents/detail/1351364
Dupont, J., Dedeyne, L., Dalle, S., Koppo, K., & Gielen, E. (2019). The Role of Omega-3 in the Prevention and Treatment of Sarcopenia. Aging Clinical and Experimental Research, 31, 825–836. https://doi.org/10.1007/s40520-019-01146-1
Dutta, B. (2015). Study of Secondary Metabolite Constituents and Curcumin Contents of Six Different Species of Genus Curcuma. Journal of Medicinal Plants Studies, 3(5), 116–119. Retrieved from https://www.plantsjournal.com/archives/
/vol3issue5/PartB/3-5-10.pdf
Eckel, R. H., & Cornier, M. (2014). Update on the NCEP ATP-III Emerging Cardiometabolic Risk Factors. BMC Medicine, 12(115), 1–9. Retrieved from http://www.biomedcentral.com/1741-7015/12/1
Esser, N., Legrand-poels, S., Piette, J., Scheen, A. J., & Paquot, N. (2014). Inflammation as a Link between Obesity, Metabolic Syndrome, and Type 2 Diabetes. Diabetes Research and Clinical Practice, 1–25. https://doi.org/10.1016/j.diabres.2014.04.006
García-Barrado, M. J., Iglesias-Osma, M. C., Pérez-García, E., Carrero, S., Blanco, E. J., Carretero-Hernández, M., & Carretero, J. (2020). Role of Flavonoids in the Interactions Among Obesity, Inflammation, and Autophagy. Pharmaceuticals, 13(342), 1–26. https://doi.org/10.3390/ph13110
Gu, C., Suleria, H. A. R., Dunshea, F. R., & Howell, K. (2020). Dietary Lipids Influence Bioaccessibility of Polyphenols from Black Carrots and Affect Microbial Diversity under Simulated Gastrointestinal Digestion. Antioxidants, 9(762), 1–17. https://doi.org/10.3390/antiox9080762
Harmain, R. M., & Dali, F. A. (2017). Buku Ajar Ilabulo Ikan Patin (Pangasius, sp.). Gorontalo: UNG Press Gorontalo.
Hasan, H., Thomas, N. A., Hiola, F., Ramadhani, F. N., & Ibrahim, P. A. S. (2022). Skrining Fitokimia dan Uji Aktivitas Antioksidan Kulit Batang Matoa (Pometia pinnata) dengan Metode 1, 1-Diphenyl-2 picrylhidrazyl (DPPH). Indonesian Journal of Pharmaceutical Education (e-Journal), 2(1), 52–66. https://doi.org/10.37311/ijpe.v2i1.10995
Hidayaturrahmah, H., Santoso, H. B., & Nurlely, N. (2017). Profil Glukosa Darah Tikus Putih Setelah Pemberian Ekstrak Minyak Ikan Patin (Pangasius hypopthalmus) sebagai Alternatif Antidiabetes. Jurnal Pharmascience, 04(02), 219–226. http://dx.doi.org/10.20527/jps.v4i2.5775
Hrebień-Filisińska, A. (2021). Application of Natural Antioxidants in the Oxidative Stabilization of Fish Oils: A Mini-Review. Journal of Food Processing and Preservation, 45(e15342), 1–12. https://doi.org/10.1111/jfpp.15342
Islam, A., Islam, S., Rahman, K., Uddin, N., & Akanda, R. (2020). The Pharmacological and Biological Roles of Eriodictyol. Archives of Pharmacal Research, 1–11. https://doi.org/10.1007/s12272-020-01243-0
Julianto, T. S. (2019). Fitokimia Tinjauan Metabolit Sekunder dan Skrining fitokimia. Jakarta: Penerbit buku kedokteran EGC.
Kawasaki, K., Muroyama, K., Yamamoto, N., & Murosaki, S. (2015). A Hot Water Extract of Curcuma longa Inhibits Adhesion Molecule Protein Expression and Monocyte Adhesion to TNF-α-Stimulated Human Endothelial Cells. Bioscience, Biotechnology, and Biochemistry, 79(10), 1654–1659. https://doi.org/10.1080/09168451.201
1039480
Keane, K. N., Cruzat, V. F., Carlessi, R., Jr., P. I. H. de B., & Newsholme, P. (2015). Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and ? -Cell Dysfunction. Oxidative Medicine and Cellular Longevity, 1–15. https://doi.org/10.1155/2015/181643
Kim, E., Davidson, L. A., Zoh, R. S., Hensel, M. E., Salinas, M. L., Patil, B. S., Jayaprakasha, G. K., Callaway, E. S., Allred, C. D., Turner, N. D., Weeks, B. R., & Chapkin, R. S. (2016). Rapidly Cycling Lgr5 + Stem Cells Are Exquisitely Sensitive to Extrinsic Dietary Factors That Modulate Colon Cancer Risk. Cell Death and Disease, 7(e2460), 1–14. https://doi.org/10.1038/cddis.2016.269
Kotha, R. R., & Luthria, D. L. (2019). Curcumin: Biological, Pharmaceutical, Nutraceutical, and Analytical Aspects. Molecules, 24(2930), 1–27. https://doi.org/10.3390/molecules24162930
Lawler, J. M., Garcia-villatoro, E. L., Guzzoni, V., Hord, J. M., Botchlett, R., Holly, D., Lawler, M. S., Gomes, M. J., Ryan, P., Rodriguez, D., Kuczmarski, J. M., Fluckey, J. D., & Talcott, S. (2018). Effect of Combined Fish Oil & Curcumin on Murine Skeletal Muscle Morphology and Stress Response Proteins During Mechanical Unloading. Nutrition Research, 65, 17–28. https://doi.org/10.1016/j.nutres.2018.12.013
Lima, R. A. M., Ferraz, S. M. M., Cardoso, V. G. K., Teixeira, C. A., & Hantao, L. W. (2023). Authentication of Fish Oil (Omega-3) Supplements Using Class-Oriented Chemometrics and Comprehensive Two-Dimensional Gas Chromatography Coupled to Mass Spectrometry. Analytical and Bioanalytical Chemistry, 415, 2601–2611. https://doi.org/10.1007/s00216-022-04428-2
Llano, S. M., Gómez, A. M., & Duarte-Correa, Y. (2022). Effect of Drying Methods and Processing Conditions on the Quality of Curcuma longa Powder. Processes, 10(702), 1–15. https://doi.org/10.3390/pr10040702
Manthey-Karl, M., Lehmann, I., Ostermeyer, U., & Schröder, U. (2016). Natural Chemical Composition of Commercial Fish Species: Characterisation of Pangasius, Wild and Farmed Turbot and Barramundi. Foods, 5(58), 1–14. https://doi.org/10.3390/foods5030058
Martínez, N., Herrera, M., Frías, L., Provencio, M., Pérez‑Carrión, R., Díaz, V., Morse, M., & Crespo, M. C. (2018). A Combination of Hydroxytyrosol, Omega ‑3 Fatty Acids and Curcumin Improves Pain and Inflammation Among Early Stage Breast Cancer Patients Receiving Adjuvant Hormonal Therapy: Results of a Pilot Study. Clinical and Translational Oncology, 21, 489–498. https://doi.org/10.1007/s12094-018-1950-0
Méndez, L., & Medina, I. (2021). Polyphenols and Fish Oils for Improving Metabolic Health: A Revision of the Recent Evidence for Their Combined Nutraceutical Effects. Molecules, 26(2438), 1–24. https://doi.org/10.3390/molecules26092438
Mohajeri, M., Behnam, B., Tasbandi, A., Jamialahmadi, T., & Sahebkar, A. (2021). Carbon-Based Nanomaterials and Curcumin: A Review of Biosensing Applications. In P. C. Guest (Ed.), Studies on Biomarkers and New Targets in Aging Research in Iran Focus on Turmeric and Curcumin (pp. 55–74). https://doi.org/10.1007/978-3-030-56153-6_4
Nasution, A. Y., Novalia, W., & Sari, D. A. (2021). Evaluasi Karakteristik Minyak Ikan Patin (Pangasius hypophthalmus) dengan Penambahan Ekstrak Kunyit sebagai Antioksidan Alami. Jurnal Ilmiah Farmasi Farmasyifa, 4(2), 22–28. https://doi.org/10.29313/jiff.v4i2.6915
Nurcahyanti, A. D. R., Cokro, F., Wulanjati, M. P., Mahmoud, M. F., Wink, M., & Sobeh, M. (2022). Curcuminoids for Metabolic Syndrome : Meta-Analysis Evidences Toward Personalized Prevention and Treatment Management. Frontiers in Nutrition, 9(June), 1–19. https://doi.org/10.3389/fnut.2022.891339
Pahlavani, M., Ramalho, T., Koboziev, I., Lemieux, M. J., Jayarathne, S., Ramalingam, L., Filgueiras, L. R., & Moustaid-moussa, N. (2020). Adipose Tissue Inflammation in Insulin Resistance: Review of Mechanisms Mediating Anti-Inflammatory Effects of Omega-3 Polyunsaturated Fatty Acids. J Investig Med, 65(7), 1021–1027. https://doi.org/10.1136/jim-2017-000535
Park, J., Do, S., Lee, M., Ha, S., & Lee, K.-G. (2022). Preparation of Turmeric Powder with Various Extraction and Drying Methods. Chemical and Biological Technologies in Agriculture, 9(39), 1–9. https://doi.org/10.1186/s40538-022-00307-1
Parunyakul, K., Srisuksai, K., Santativongchai, P., Pongchairerk, U., Ampawong, S., Tulayakul, P., & Fungfuang, W. (2022). The First Study on the Effect of Crocodile Oil from Crocodylus siamensis on Hepatic Mitochondrial Function for Energy Homeostasis in Rats. Veterinary World, 15(4), 986–997. https://doi.org/10.14202/vetworld.2022.986-997
Ramírez-Moreno, E., Arias-Rico, J., Jiménez-Sánchez, R. C., Estrada-Luna, D., Jiménez-Osorio, A. S., Zafra-Rojas, Q. Y., Ariza-Ortega, J. A., Flores-Chávez, O. R., Morales-Castillejos, L., & Sandoval-Gallegos, E. M. (2022). Role of Bioactive Compounds in Obesity : Metabolic Mechanism Focused on Inflammation. Foods, 11(1232), 1–23. https://doi.org/10.3390/foods11091232
Reski, S., Mundhofir, F. E. P., Murbawani, E. A., Nindita, Y., Muniroh, M., Swastawati, F., & Mahati, E. (2021). Efficacy of Catfish (Pangasius Hypophthalmus) Oil to Overcome Stunting by Reducing Inflammatory Condition. International Journal of Pharmacy and Pharmaceutical Sciences, 13(5), 18–22. https://doi.org/10.22159/ijpps.2021v13i5.40357
Rezki, R. S., Anggoro, D., & Mz, S. (2015). Ekstraksi Multi Tahap Kurkumin dari Kunyit (Curcuma domestica Valet) Menggunakan Pelarut Etanol. Jurnal Teknik Kimia USU, 4(3), 29–34. https://doi.org/10.32734/jtk.v4i3.1478
Rochlani, Y., Pothineni, N. V., Kovelamudi, S., & Mehta, J. L. (2017). Metabolic Syndrome: Pathophysiology, Management, and Modulation by Natural Compounds. Therapeutic Advances in Cardiovascular Disease, 11(8), 215–225. https://doi.org/10.1177/1753944717711379
Sá, R. D. C. da C. de., Cruz, M. M., Farias, T. M. de., Silva, V. S. da., Simão, J. de J., Telles, M. M., & Alonso-Vale, M. I. C. (2020). Fish Oil Reverses Metabolic Syndrome, Adipocyte Dysfunction, and Altered Adipokines Secretion Triggered by High-Fat Diet-Induced Obesity. Physiological Reports, 8(e14380), 1–13. https://doi.org/10.14814/phy2.14380
Saklayen, M. G. (2018). The Global Epidemic of the Metabolic Syndrome. Current Hypertension Reports, 20(12), 1–8. https://doi.org/10.1007/s11906-018-0812-z
Sari, R. N., Utomo, B. S. B., Basmal, J., & Hastarini, E. (2016). Pemurnian Minyak Ikan Patin dari Hasil Samping Pengasapan Ikan. Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan, 11(2), 171–182. https://doi.org/10.15578/jpbkp.v11i2.224
Sasanfar, B., Toorang, F., & Salehi-Abarghouei, A. (2024). Effects of n‑3 Polyunsaturated Fatty Acid Supplementation on Appetite: A Systematic Review and Meta‑Analysis of Controlled Clinical Trials. Systematic Reviews, 13(44), 1–11. https://doi.org/10.1186/s13643-023-02430-y
Sembiring, L., Ilza, M., & Diharmi, A. (2018). Karateristik Minyak Murni dari Lemak Perut Ikan Patin (Pangasius hypophthalmus) dan Dipurifikasi dengan Bentonite. Jurnal Pengolahan Hasil Perikanan Indonesia, 21(3), 549–555. Retrieved from https://journal.ipb.ac.id/index.php/jphpi/article/download/24742/16119/
Shahidi, F., & Ambigaipalan, P. (2018). Omega-3 Polyunsaturated Fatty Acids and Their Health Benefits. Annual Review OfFood Science and Technology, 9, 345–381. https://doi.org/10.1146/annurev-food-111317- 095850
Shehadeh, M. B., Suaifan, G. A. R. Y., & Abu-Odeh, A. M. (2021). Plants Secondary Metabolites as Blood Glucose- Lowering Molecules. Molecules, 26(4333), 1–46. https://doi.org/10.3390/molecules26144333
Sokamte, T. A., Mbougueng, P. D., Mohammadou, B. A., Tatsadjieu, N. L., & Sachindra, N. M. (2020). Proximal Composition and Fatty Acid Profile of Fresh and Smoked Fillets of Pangasius hypophthalmus. Scientific African, 9(e00534), 1–9. https://doi.org/10.1016/j.sciaf.2020.e00534
Spencer, M., Finlin, B. S., Unal, R., Zhu, B., Morris, A. J., Shipp, L. R., Lee, J., Walton, R. G., Adu, A., Erfani, R., Campbell, M., Jr, R. E. M., Peterson, C. A., & Kern, P. A. (2013). Omega-3 Fatty Acids Reduce Adipose Tissue Macrophages in Human Subjects With Insulin Resistance. Diabetes, 62, 1709–1717. https://doi.org/10.2337/db12-1042
Suaifan, G. A. R. Y., Shehadeh, M. B., Darwish, R. M., Al-ijel, H., & Abbate, V. (2015). Design, Synthesis and in Vivo Evaluation of Novel Glycosylated Sulfonylureas as Antihyperglycemic Agents. Molecules, 20, 20063–20078. https://doi.org/10.3390/molecules201119676
Sulistyaningrum, H., Swastawati, F., Mexitalia, M., & Noer, E. R. (2021). Catfish Oil (Pangasius hypophthalmus) Effect to Ferritin and sTfR in Iron Deficiency Anemia. Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition), 10(1), 28–35. https://doi.org/10.14710/jgi.10.1.28-35
Suryawanshi, H., Naik, R., Kumar, P., & Gupta, R. (2017). Curcuma Longa Extract – Haldi: A Safe, Eco‑Friendly Natural Cytoplasmic Stain. Journal of Oral and Maxillofacial Pathology, 21(3), 340–344. https://doi.org/10.4103/jomfp.JOMFP_62_17
Suseno, S. H., Rizkon, A. K., Jacoeb, A. M., Nurjanah, N., & Supinah, P. (2020). Ekstraksi Dry Rendering dan Karakterisasi Minyak Ikan Patin (Pangasius sp.) Hasil Samping Industri Filet di Lampung. Jurnal Pengolahan Hasil Perikanan Indonesia, 23(1), 38–46. https://doi.org/10.17844/jphpi.v23i1.30722
Tanvir, E. M., Hossen, S., Hossain, F., Afroz, R., Gan, S. H., Khalil, I., & Karim, N. (2017). Antioxidant Properties of Popular Turmeric (Curcuma longa) Varieties from Bangladesh. Journal of Food Quality, 1–9. https://doi.org/10.1155/2017/8471785
Tortosa-caparrós, E., Navas-carrillo, D., Marín, F., & Orenes-piñero, E. (2016). Anti-Inflammatory Effects of Omega 3 and Omega 6 Polyunsaturated Fatty Acids in Cardiovascular Disease and Metabolic Syndrome. Critical Reviews in Food Science and Nutrition, 57(16), 3421–3429. https://doi.org/10.1080/10408398.2015.1126549
U.S. Department of Health and Human Services & U.S. Department of Agriculture. (2015). Dietary Guidelines For Americans 2015-2020 (8th ed.). Retrieved from https://health.gov/our-work/food-nutrition/previous-dietary-guidelines
/2015
Uchio, R., Muroyama, K., Okuda-Hanafusa, C., Kawasaki, K., Yamamoto, Y., & Murosaki, S. (2019). Hot Water Extract of Curcuma longa L. Improves Serum Inflammatory Markers and General Health in Subjects with Overweight or Prehypertension/Mild Hypertension: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients, 11(1822), 1–17. https://doi.org/10.3390/nu11081822
Uchio, R., Okuda-Hanafusa, C., Saji, R., Kawasaki, K., Muroyama, K., Murosaki, S., Yamamoto, Y., & Hirose, Y. (2022). A Hot Water Extract of Curcuma longa L. Improves Fasting Serum Glucose Levels in Participants with Low-Grade Inflammation: Reanalysis of Data from Two Randomized, Double-Blind, Placebo-Controlled Trials. Nutrients, 14(18). https://doi.org/10.3390/nu14183763
Venkateshwari, T., Ganapathy, S., Arulmari, R., & Vijayakumary, P. (2021). Effect of Drying Temperature on the Curcumin Content of Turmeric Rhizomes (Curcuma longa L.). The Pharma Innovation Journal, 10(10), 2349–2351. Retrieved from http://www.thepharmajournal.
com
Xu, F., Fan, W., Wang, W., Tang, W., Yang, F., Zhang, Y., Cai, J., Song, L., & Zhang, C. (2018a). Effects of Omega-3 Fatty Acids on Metabolic Syndrome in Patients with Schizophrenia : A 12-Week Randomized Placebo-Controlled Trial. Psychopharmacology, 236, 1273–1279. https://doi.org/10.1007/s00213-018-5136-9
Xu, L., Li, Y., Dai, Y., & Peng, J. (2018b). Natural Products for the Treatment of Type 2 Diabetes Mellitus: Pharmacology and Mechanisms. Pharmacological Research, 130, 451-465. https://doi.org/10.1016/j.phrs.2018.01.015
Yi, T., Li, S. M., Fan, J. Y., Fan, L. L., Zhang, Z. F., Luo, P., Zhang, X. J., Wang, J. G., Zhu, L., Zhao, Z. Z., & Chen, H. B. (2014). Comparative Analysis of EPA and DHA in Fish Oil Nutritional Capsules by GC-MS. Lipids in Health and Disease, 13(190), 1–6. https://doi.org/10.1186/1476-511X-13-190
Author Biographies
Helvi Desi Mambaya, Departement of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia
Muflihatul Muniroh, Departement of Physiology, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia
Muhammad Sulchan, Departement of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia
Diana Nur Afifah, Departement of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia
License
Copyright (c) 2024 Helvi Desi Mambaya, Muflihatul Muniroh, Muhammad Sulchan, Diana Nur Afifah
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with Jurnal Penelitian Pendidikan IPA, agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution 4.0 International License (CC-BY License). This license allows authors to use all articles, data sets, graphics, and appendices in data mining applications, search engines, web sites, blogs, and other platforms by providing an appropriate reference. The journal allows the author(s) to hold the copyright without restrictions and will retain publishing rights without restrictions.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in Jurnal Penelitian Pendidikan IPA.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).