Caspase 3 and Caspase 10 Expression in Rat Muscles Post Gagatan Harimau (Paraboea leuserensis B.L.Burtt) Nanoherbal and Exercise

Authors

Ashfira , Syafruddin Ilyas , Masitta Tanjung

DOI:

10.29303/jppipa.v10i9.8371

Published:

2024-09-25

Issue:

Vol. 10 No. 9 (2024): September

Keywords:

Caspase 3, Caspase 10, Gagatan harimau, Nanoherbal, Physical exercise

Research Articles

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Ashfira, Ilyas, S., & Tanjung, M. (2024). Caspase 3 and Caspase 10 Expression in Rat Muscles Post Gagatan Harimau (Paraboea leuserensis B.L.Burtt) Nanoherbal and Exercise. Jurnal Penelitian Pendidikan IPA, 10(9), 7010–7017. https://doi.org/10.29303/jppipa.v10i9.8371
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Abstract

This study aims to analyze the Expression of Caspase 3 and Caspase 10 in Rat Muscles Post Gagatan Harimau (Paraboea leuserensis B.L.Burtt) Nanoherbal and Exercise. Treatment consists of control group, maximum physical exercise, maximum physical exercise + Vitamin C at a dose of 2 mg/Kg Body Weight, maximum physical exercise + Gagatan Harimau nanoherbal with concentration 100, 125 and 150 mg/Kg BW. Data obtained from each observation parameter were recorded and presented in table and figure form. The data were analyzed using SPSS software version 25 with significant differences at 5%. The results of the study showed all treatments (p<0.05) in the expression of caspase 3 and caspase 10 in rat muscle. At dose of 150 mg/Kg BW can reduce the expression of caspase 3 and caspase 10 in rat muscle. Induction of Gagatan Harimau leaf nanoherbal as an antioxidant in male rats given swimming physical exercise showed improvements in muscle histology and morphology. A dose of 150 mg/Kg BW of nanoherbal Gagatan Harimau leaves was the best dose because it showed cell regeneration close to the normal treatment group.

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Author Biographies

Ashfira, Universitas Sumatera Utara

Syafruddin Ilyas, Universitas Sumatera Utara

Masitta Tanjung, Universitas Sumatera Utara

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Copyright (c) 2024 Ashfira, Syafruddin Ilyas, Masitta Tanjung

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