Comparison of the Effects of Injectable and Implant Progestin Contraceptive Agents on Weight Increase Based on Body Mass Index (BMI) in Family Planning Acceptors in District

Authors

Sukarni Setya Yuningsih , Atika Juliarni , Desti Indayani , Mega Yanti Erdha , Milda Anggraini , Nur Afni

DOI:

10.29303/jppipa.v10i12.8974

Published:

2024-12-21

Issue:

Vol. 10 No. 12 (2024): In Progress

Keywords:

Birth Control Septor, BMI, Implants, Progestin Injection, Weight

Research Articles

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Yuningsih, S. S., Juliarni, A., Indayani, D., Erdha, M. Y., Anggraini, M., & Afni, N. (2024). Comparison of the Effects of Injectable and Implant Progestin Contraceptive Agents on Weight Increase Based on Body Mass Index (BMI) in Family Planning Acceptors in District. Jurnal Penelitian Pendidikan IPA, 10(12), 10226–10230. https://doi.org/10.29303/jppipa.v10i12.8974

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Abstract

Weight gain is one of the side effects that birth control acceptors often worry about, especially users of hormonal methods such as progestin injections and implants. This concern is reasonable because several studies show that the use of hormonal contraception can increase the risk of weight gain. This study aims to compare the use of progestin injections and implants on weight gain based on Body Mass Index (BMI) in family planning acceptors in Muara Enim Regency in 2024. The research sample consists of 266 respondents who are acceptors of birth control injections and implants, with an observational analytical research design using a case control design. The sample size was determined using the G-Power Software application Version 3.1.6 with correlation and regression tests. The results of the analysis show that family planning acceptors with progestin injectable contraceptives have a 1.68 times greater chance of experiencing abnormal weight gain (obesity) compared to family planning acceptors who use implants (95% CI 1.021-2.752). It is hoped that the results of this research can be used as a reference for midwives to provide education regarding the negative impact of weight gain on family planning acceptors, so that they can inform more appropriate hormonal contraceptive choices.

References

Achilles, S. L., Mhlanga, F. G., Musara, P., Poloyac, S. M., Chirenje, Z. M., & Hillier, S. L. (2018). Misreporting of contraceptive hormone use in clinical research participants. Contraception, 97(4), 346–353. https://doi.org/10.1016/j.contraception.2017.09.013

Andreoli, L., Guadagni, I., Picarelli, G., & Principi, M. (2024). Comprehensive reproductive healthcare for women with immune-mediated inflammatory diseases: Addressing rheumatoid arthritis, spondyloarthritis and inflammatory bowel disease through life’s stages. Autoimmunity Reviews, 23(3), 103507. https://doi.org/10.1016/j.autrev.2023.103507

Bick, A. J., Louw-du Toit, R., Skosana, S. B., Africander, D., & Hapgood, J. P. (2021). Pharmacokinetics, metabolism and serum concentrations of progestins used in contraception. Pharmacology and Therapeutics, 222, 107789. https://doi.org/10.1016/j.pharmthera.2020.107789

Bistervels, I. M., Scheres, L. J. J., Hamulyák, E. N., & Middeldorp, S. (2019). Sex matters: Practice 5P’s when treating young women with venous thromboembolism. Journal of Thrombosis and Haemostasis, 17(9), 1417–1429. https://doi.org/10.1111/jth.14549

Bonny, A., Britto, M., Huang, B., Succop, P., & Slap, G. (2002). Predictors of weight gain among adolescent females on depomedroxyprogesterone acetate (DMPA). Journal of Adolescent Health, 30(2), 94. https://doi.org/10.1016/s1054-139x(01)00348-2

Chabbert-Buffet, N., Marret, H., Agostini, A., Cardinale, C., Hamdaoui, N., Hassoun, D., Jonville-Bera, A. P., Lambert, M., Linet, T., Pienkowski, C., Plu-Bureau, G., Pragout, D., Robin, G., Jablonski, C. R., Schefler, M., Vidal, F., Vigoureux, S., & Hédon, B. (2019). Clinical practice guidelines for contraception by the French National College of Gynecologists and Obstetricians (CNGOF). Journal of Gynecology Obstetrics and Human Reproduction, 48(7), 441–454. https://doi.org/10.1016/j.jogoh.2019.04.009

Cipriani, S., Todisco, T., Scavello, I., Di Stasi, V., Maseroli, E., & Vignozzi, L. (2020). Obesity and hormonal contraception: an overview and a clinician’s practical guide. Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, 25(5), 1129–1140. https://doi.org/10.1007/s40519-019-00774-w

Franasiak, J. M., Alecsandru, D., Forman, E. J., Gemmell, L. C., Goldberg, J. M., Llarena, N., Margolis, C., Laven, J., Schoenmakers, S., & Seli, E. (2021). A review of the pathophysiology of recurrent implantation failure. Fertility and Sterility, 116(6), 1436–1448. https://doi.org/10.1016/j.fertnstert.2021.09.014

Halpern, V., Brache, V., Taylor, D., Lendvay, A., Cochón, L., Jensen, J. T., & Dorflinger, L. J. (2021). Clinical trial to evaluate pharmacokinetics and pharmacodynamics of medroxyprogesterone acetate after subcutaneous administration of Depo-Provera. Fertility and Sterility, 115(4), 1035–1043. https://doi.org/10.1016/j.fertnstert.2020.11.002

Lindley, K. J., Bairey Merz, C. N., Davis, M. B., Madden, T., Park, K., & Bello, N. A. (2021). Contraception and Reproductive Planning for Women With Cardiovascular Disease: JACC Focus Seminar 5/5. Journal of the American College of Cardiology, 77(14), 1823–1834. https://doi.org/10.1016/j.jacc.2021.02.025

Matahari, R., Utami, F. P., & Sugiharti, S. (2019). Buku Ajar Keluarga Berencana Dan Kontrasepsi. Pustaka Ilmu.

Mulvagh, S. L., Mullen, K. A., Nerenberg, K. A., Kirkham, A. A., Green, C. R., Dhukai, A. R., Grewal, J., Hardy, M., Harvey, P. J., Ahmed, S. B., Hart, D., Levinsson, A. L. E., Parry, M., Foulds, H. J. A., Pacheco, C., Dumanski, S. M., Smith, G., & Norris, C. M. (2022). The Canadian Women’s Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women — Chapter 4: Sex- and Gender-Unique Disparities: CVD Across the Lifespan of a Woman. CJC Open, 4(2), 115–132. https://doi.org/10.1016/j.cjco.2021.09.013

Nelson, H. D., Cantor, A., Jungbauer, R. M., Eden, K. B., Darney, B., Ahrens, K., Burgess, A., Atchison, C., Goueth, R., & Fu, R. (2022). Effectiveness and Harms of Contraceptive Counseling and Provision Interventions for Women. Annals of Internal Medicine, 175(7), 980–993. https://doi.org/10.7326/M21-4380

Nurmainah, N., Wahdaningsih, S., & Innas, S. Q. (2020). Analisis Pengaruh Penggunaan Depot Medroxyprogesterone Acetate Terhadap Kenaikan Berat Badan Akseptor di Puskesmas Perumnas II Pontianak. Jurnal Pharmascience, 7(2), 149. https://doi.org/10.20527/jps.v7i2.8400

Patmahwati, P. (2019). Perbandingan Indeks Massa Tubuh Antara Akseptor Suntik Hormonal Dengan Implant Di Puskesmas Wara Selatan Kota Palopo. Voice of Midwifery, 9(1), 813–822. https://doi.org/10.35906/vom.v9i1.84

Rocca, M. L., Palumbo, A. R., Visconti, F., & Di Carlo, C. (2021). Safety and Benefits of Contraceptives Implants: A Systematic Review. Pharmaceuticals, 14(6), 548. https://doi.org/10.3390/ph14060548

Stempak-Droissart, T., Rousset-Jablonski, C., Spritzer, P. M., Lalhou, N., Larger, E., Pichard, C., Plessier, A., & Gompel, A. (2022). Impact of vascular liver disease on the menstrual cycle and metabolic status in premenopausal women. Clinics and Research in Hepatology and Gastroenterology, 46(1), 1–23. https://doi.org/10.1016/j.clinre.2021.101756

Todd, C. S., Lorenzetti, L., Mussa, A., Ridgeway, K., Morroni, C., & Nanda, K. (2024). Drug-drug interactions between antiretrovirals and hormonal contraception: An updated systematic review. Contraception, 138, 110490. https://doi.org/10.1016/j.contraception.2024.110490

Wahyuni, E. S. (2016). Efek Paparan Depo Progestin Terhadap Hormon Pengatur Nafsu Makan (LEPTIN) Dan Berat Badan Pada Tikus Putih Betina. Jurnal Kebidanan Indonesia, 7(1). https://doi.org/10.36419/jkebin.v7i1.46

Yusran, A. M., Nurmainah, N., & Andrie, M. (2022). Analisis Hubungan Penggunaan Kontrasepsi Hormonal dengan Obesitas dan Hiperkolesterolemia di Puskesmas Pal III Pontianak. Jurnal Pharmascience, 9(1), 132. https://doi.org/10.20527/jps.v9i1.11697

Author Biographies

Sukarni Setya Yuningsih, Sekolah Tinggi Ilmu Kesehatan Abdi Nusantara

Atika Juliarni, Sekolah Tinggi Ilmu Kesehatan Abdi Nusantara

Desti Indayani, Sekolah Tinggi Ilmu Kesehatan Abdi Nusantara

Mega Yanti Erdha, Sekolah Tinggi Ilmu Kesehatan Abdi Nusantara

Milda Anggraini, Sekolah Tinggi Ilmu Kesehatan Abdi Nusantara

Nur Afni, Sekolah Tinggi Ilmu Kesehatan Abdi Nusantara

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Copyright (c) 2024 Sukarni Setya Yuningsih, Atika Juliarni, Desti Indayani, Mega Yanti Erdha, Milda Anggraini, Nur Afni

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